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通心络对冠心病患者血管内皮依赖性舒张功能的影响
引用本文:陈德明,郭文涛,李云富,党彦平,丁学智,耿壮丽.通心络对冠心病患者血管内皮依赖性舒张功能的影响[J].实用全科医学,2005,3(1):20-21.
作者姓名:陈德明  郭文涛  李云富  党彦平  丁学智  耿壮丽
作者单位:河南省鹤壁市第一人民医院心内科 458000(陈德明,郭文涛,李云富,党彦平,丁学智),河南省鹤壁市第一人民医院心内科 458000(耿壮丽)
摘    要:目的 观察通心络对冠心病患者 (CHD)血管内皮依赖性舒张功能的影响。方法 应用高分辨率血管外超声检测通心络胶囊治疗 80例冠心病患者 12周前后肱动脉内皮依赖性血管舒张功能 ,与对照组 80例比较。结果 治疗组12周前后血流介导的内皮依赖性血管舒张功能明显增加 (4 .1± 10 .5 ) % :(8.7± 1.0 ) % ] (P <0 .0 1) ,对照组 12周前后无显著意义 (4 .1± 1.2 ) % :(4 .3± 1.0 ) % ] (P >0 .0 5 )。结论 通心络胶囊具有改善血管内皮依赖性舒张功能。

关 键 词:冠心病患者  血管内皮依赖性舒张功能  通心络胶囊  内皮依赖性血管舒张功能  对照组  治疗组  肱动脉  血流介导  影响  CHD
修稿时间:2004年4月4日

Effect of Tongxinluo on endothelium- dependent vasodilatation function in patients with Coronary Artery Disease
CHEN Deming,GUO Wentao,LI Yunfu,et al..Effect of Tongxinluo on endothelium- dependent vasodilatation function in patients with Coronary Artery Disease[J].Applied Journal Of General Practice,2005,3(1):20-21.
Authors:CHEN Deming  GUO Wentao  LI Yunfu  
Institution:CHEN Deming,GUO Wentao,LI Yunfu,et al. Depa rtment of Internal Medicine,The first people's hospital of Hebi,Henan 458000
Abstract:Objective To observe the effect of Tongxinlu o on endothelium-depen dent vasodilatation function in patients with CAD. Methods T he patients in exp erimental group (80 cases) were treated with Tongxinluo capsules. Endothelium-de pendent vasodilatation function was detected by ultrasound examination before an d after the treatment. The endothelium-dependent vasodilatation function in two groups was compared. Results After 12-weeks treatment, the e ndothelium-depende nt vasodilatation function increased significantly in experimental group (P <0.01 ). There was no significant difference in control group before and after treatme nt (P>0.05). Conclusions Tongxinluo capsule can improve the endothelium-dependent vasodilatation function.
Keywords:Tongxinluo  Endothelium-dependent vasodilatation  function  Blood vessel
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