模拟失重状态对情绪稳定性影响的磁共振脑功能成像研究

目的应用功能性磁共振（functional magnetic resonance imaging，fMRI）扫描观察模拟失重对情绪稳定性的影响。方法选取8名航天志愿者完成卧床3周的模拟失重实验。实验前后使用fMRI行功能性磁共振扫描测试。实验采用恐惧情绪图片刺激。结果卧床前，在完成任务时，双侧枕叶枕中回、枕叶楔叶、双侧额叶额中回及双侧丘脑出现显著的脑激活区；双侧边缘叶海马旁回及右侧杏仁核出现了小范围的激活区。卧床后进行同一任务扫描，激活脑区的范围及信号强度与卧床前相似。结论模拟失重状态后，对情绪激发图片反应的脑区激活模式与模拟失重状态前较为接近。说明模拟失重状态对航天训练员情绪稳定性的影响较小。

Application of functional magnetic resonance imaging in showing the effect of simulated weightlessness on emotional stability

Objective To study the application of functional magnetic resonance imaging （fMRI） in showing the effect of simulated weightlessness on emotional stability. Methods Eight male astronaut volunteers underwent stimulated weightlessness experiments in bed for 3 weeks, followed by fMRI. Results Significantly activated areas were observed in bilateral mid-occipital gyrus, occipital cuneus, bilateral mid-frontal gyrus of prefrontal and bilateral thalamus, and a small activated area appeared in bilateral limbic lobe subiculum hippocampi and right amygdaloid nuclei at simulated weightlessness experiments before lying in bed. The size and signal intensity of activated brain were similar at simulated weightlessness experiments before and after lying in bed. Conclusion The effect of stimulated weightlessness is similar on emotional stability of astronaut volunteers.