| 螺旋断层放疗45例鼻咽癌近期临床观察 |
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| 引用本文： | 杜镭,马林,周桂霞,冯林春,曲宝林,徐寿平,谢传滨.螺旋断层放疗45例鼻咽癌近期临床观察[J].军医进修学院学报,2009,30(3):311-314. |
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| 作者姓名： | 杜镭 马林 周桂霞 冯林春 曲宝林 徐寿平 谢传滨 |
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| 作者单位： | 解放军总医院,放疗科,北京,100853 |
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| 摘 要： | 目的：探讨螺旋断层放疗鼻咽癌的经验及近期临床观察结果。方法：观察2007年9月-2008年9月我院收治的经螺旋断层放疗的鼻咽癌患者45例,鼻咽癌原发病灶（pGTVnx）及转移性淋巴结（GTVnd）处方剂量70～76Gy/32～33F,高危区（CTV1）60～66Gy/32～33F,低危区（CTV2）49.5～56.1Gy/32～33F。根据RTOG/EORTC标准评价急性反应。结果：随访时间1～12个月,中位随访时间6个月。皮肤急性反应发生率1级75.6%、2级17.8%、3级2.2%;口腔黏膜急性反应发生率1～2级97.8%,3级2.2%;急性腮腺损伤发生率1级48.9%,2级46.7%,无3级损伤。鼻咽原发灶和颈部转移淋巴结消退率分别为88.9%和90.0%,无肿瘤进展及局部复发。结论：鼻咽癌螺旋断层放疗严重急性反应发生率低,且治疗时间短。
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| 关 键 词： | 鼻咽肿瘤 放射疗法 调强适形 急相反应 |
Short-term clinical observation of tomotherapy for 45 nasopharyngeal carcinoma patients |
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| DU Lei,MA Lin,ZHOU Gui-xia,FENG Lin-chun,QU Bao-lin,XU Shou-ping,XIE Chuan-bin.Short-term clinical observation of tomotherapy for 45 nasopharyngeal carcinoma patients[J].Academic Journal of Pla Postgraduate Medical School,2009,30(3):311-314. |
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| Authors: | DU Lei MA Lin ZHOU Gui-xia FENG Lin-chun QU Bao-lin XU Shou-ping XIE Chuan-bin |
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| Institution: | Department of Radiation Oncology;Chinese PLA General Hospital;Beijing 100853;China |
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| Abstract: | Objective:To evaluate the preliminary clinical results of tomotherapy for 45 nasopharyngeal carcinoma(NPC) patients.Methods:Between September 2007 and September 2008,45 newly diagnosed NPC patients were treated with tomotherapy at the dose of 70-76Gy/32-33F for the gross tumor volume(pGTVnx) and positive lymph nodes(GTVnd),and 60-66Gy/32-33F for the high risk clinical target volume(CTV1),and 49.5-56.1Gy/32-33F for the low risk clinical target volume(CTV2),respectively.Acute lesions were evaluated with the R... |
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| Keywords: | nasopharyngeal neoplasms TomoTherapy acute-phase reaction |
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