肺曲霉菌病21例临床分析

目的:提高对肺曲霉菌病的认识,制定合理治疗方案.方法:对我院21例诊断肺曲霉菌病患者的临床资料进行回顾分析.结果:所有患者均有基础疾病,长期应用糖皮质激素9例(42.9%),使用多种抗生素超过3周18例(85.7%),机械通气9例(42.9%),深静脉置管8例(38%),白细胞减少6例(28.6%).其中,过敏型肺曲霉菌病3例(14.3%);寄生型肺曲霉菌病5例(23.8%);侵袭型肺曲霉菌病13例(61.9%).死亡5例(23.8%),治愈或好转16例(76.2%).结论:肺曲霉菌病患者多患有基础疾病,并存在多种危险因素.诊断主要根据病史、影像学表现和痰培养结果,确诊依赖于肺组织内发现曲霉菌丝.应根据肺曲霉菌病诊断分型的不同,分别选择激素、手术、药物等不同的治疗方法.

A clinical analysis of 21 cases of pulmonary aspergillosis

Objective: To promote recognition of pulmonary aspergillosis and develop appropriate clinical treatment for the disease.Methods: The clinical features of 21 cases of pulmonary aspergillosis were analyzed in our hospital.Results: All 21 patients had primary diseases.9 patients were administered glucocorticoids chronically(42.9%);18 were administered antibiotics for more than 3 weeks(85.7%);9 were treated with mechanical ventilation(42.9%);8 were treated with deep venous catheter(38%);and 6 had leucopenia(28....