血浆胃动素测定及临床初步应用

应用放免法观察了10组共249例空腹血浆MLI水平。结果各疾病之MLI值均显著高于正常对照组。60岁以上老年人MLI值略高于对照组,但增高幅度较低,其表现不同于疾病组。急性肠炎,结肠易激综合征,药源性腹泻患者之MLI值高于便秘者。各类未治疗恶性肿瘤之MLI显著高于良性胃肠道病。本文中以胃、结肠癌手术前病例及病程长糖尿病患者之MLI值最高。此外,尚观察了胃癌行迷走神经干或分支切断术后之MLI变化。

The determination of plasma MLI and its preliminary clinical investigation

Two hundred forty-nine fasting plasma samples devided into ten groups, using RIA method, were measured. The results showed that, the levels of MLI in all diseased groups were significantly higher than the normal controls. The MLI values showed a special appearence of aged adults, which was different from diseased groups. Concentrations of acute enteritis, IBS, iatrogenic diarrhea were higher than those who were diagnosed as constipation. Patients with cancers of different origen contained a higher MLI values than those with benign diseases. In this paper MLI concentrations in malignant GI tumors and diabetes showed a significant increase compared with all other groups. The cause of this phenomena remainer to be studied. Besides, different concentrations of MLI in patients with gastric carcinoma encountered of truncal and selective vagotomy during gastrectomy were also studied.