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安珐特治疗慢性乙型肝炎临床效果观察
引用本文:何延专,周耀南,覃雪英,黄其文,陆春雷.安珐特治疗慢性乙型肝炎临床效果观察[J].右江民族医学院学报,2005,27(6):791-793.
作者姓名:何延专  周耀南  覃雪英  黄其文  陆春雷
作者单位:右江民族医学院附属医院传染科,广西,百色,533000
摘    要:目的探讨治疗乙肝、抗肝纤维化的有效方法。方法对208例慢性乙型肝炎分为两组,两组综合治疗相同,在此基础上,治疗组加用安珐特(复方牛胎肝提取物片)口服治疗。观察患者治疗前后血清Ⅲ型前胶原(PC-Ⅲ)、层粘蛋白(LN)、透明质酸(HA)、Ⅳ型胶原(Ⅳ-C)、肝功能等指标的变化及疗效。结果治疗组血清肝纤维化指标(PC-Ⅲ、LN、HA、Ⅳ-C)、丙氨酸转氨酶(ALT)、天门冬氨酸转氨酶(AST)、血清总胆红素(TBil)、白蛋白(ALB)均有明显改善,与治疗前及对照组比较差异均有高度显著性(P均<0.01),治疗组临床疗效优于对照组(P<0.05)。结论安珐特具有较好的保肝和抗肝组织纤维化作用。

关 键 词:肝炎  乙型  慢性  安珐特  肝硬化  生物学标记
文章编号:1001-5817(2005)06-0791-03
收稿时间:2005-05-16
修稿时间:2005年5月16日

Clinical efficacy of An - Fa - Te in treatment of chronic hepatitis B
HE Yan - zhuan,ZHOU Yao - nan,QIN Xue - ying,HUANG Qi - wen,LU Chun - lei.Clinical efficacy of An - Fa - Te in treatment of chronic hepatitis B[J].Journal of Youjiang Medical College For Nationalities,2005,27(6):791-793.
Authors:HE Yan - zhuan  ZHOU Yao - nan  QIN Xue - ying  HUANG Qi - wen  LU Chun - lei
Institution:Department of Infectious Diseases, Affiliated Hospital of Youjiang Medical College for Nationalities, Bose, Guangxi 533000, P.R. China
Abstract:Objective To explore an effective therapeutic regimen for treatment of chronic hepatitis B and for resistance to liver fibrosis.Methods 208 patients with chronic hepatitis B were divided into two groups,a therapeutic group and a control group.The two groups received the same basic combined treatment.Moreover,the therapeutic group was orally given An-Fa-Te(compound fetal cow liver extract) as well.Before and after treatment,the indexes of serum type Ⅲ(PC-Ⅲ),hyaluronic(HA),type Ⅳ collagen(Ⅳ-C) and hepatic indexes were measured in were measured and the clinical efficacy were observed. Results In the therapeutic group,the serum liver cirrhotic indexes(PC-Ⅲ,LN,HA,and Ⅳ-C),alanine transaminase(ALT),aspartase transaminase(AST), serum total bilirubin(TBiL) and albumin(ALB) were improved after treatment.In comparison to those before treatment and those in the control group,there were statistically significant differences(P<0.01),respectively.The clinical therapeutic efficacy was better than that of the control group(P<0.05).Conclusion An-Fa-Te is more effective in protecting liver function and in resistance to the liver tissue fibrosis.
Keywords:hepatitis B  chronic  An-Fa-Te  liver cirrhosis  biological markers
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