不同程度急性低氧对家兔心电图变化的比较分析

目的　观察不同程度急性低氧对家兔心电图的影响。方法　所有的实验模型家兔中 ,以A组吸入空气为对照组 ,吸入氮氧混合气体B组为低氧 1 2 .5 %组 ,C组为低氧 8.5 %组。急性低氧时间分为 5、1 0、1 5、2 0min ,分别测定不同低氧时间的心电图变化情况。结果　两个急性低氧组心电图变化情况 :心率明显减慢 ,P波时间延长、电压降低 ;PR、QRS间期延长 ;ST段两组都抬高在基线上 ,但C组抬高较明显 ;T波电压稍降低 ;QT间期延长 ;B组R波电压较高 ,而C组较低 ;S波深度变浅。结论　急性低氧对家兔心电图的影响根据其低氧程度不同有明显的变化。

Comparative analysis of the effect of different degree acute hypoxia on the changes of electrocardiogram in rabbits

Objective To investigate the effect of different degree acute hypoxia on the electrocardiogram (ECG) in rabbits. Methods All the model rabbits were allocated to three groups: Group A (the normal control group), inhaling the air; Group B (the 12.5% hypoxia group), inhaling the mixed nitrogen oxygen gas; and Group C (the 8.5% hypoxia group), inhaling the same gas as group B. The changes of ECG were measured at different hypoxia time, i.e. 5 minutes, 10 minutes, 15 minutes and 20 minutes. Results The changes of ECG in groups B and C: The heart rate lowered significantly, P-wave time prolonged, and the electric voltage decreased, the PR and QRS intermittent prolonged. ST segments elevated at the baseline, but increased significantly in Group C. T-wave voltage decreased slightly; and QT intermittent prolonged. R wave in Group B was higher than that in Group C. The S-wave length shortened. Conclusions The effect of acute hypoxia on ECG changed significantly according to different degree of hypoxia.