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| 杨梅多酚对核辐射损伤小鼠血液系统的保护作用 | |
| 引用本文： | 汤佩莲,迟文,曾洪辉.杨梅多酚对核辐射损伤小鼠血液系统的保护作用[J].海南医学院学报,2005,11(5):391-392. |
| 作者姓名： | 汤佩莲 迟文 曾洪辉 |
| 作者单位： | 1. 广东药学院门诊部,广州,510224 2. 157医院,广州,510510 3. 广东省药物研究所门诊部,广州,510440 |
| 摘 要： | 目的:研究杨梅多酚对受核辐射损伤小鼠血液系统的保护作用,为抗核辐射损伤药物的开发提供床前药效预试。方法:采用60Co-r射线致小白鼠有形血细胞下降的动物模型。结果:杨梅多酚能提高有形血细胞计数,在杨梅多酚组和病理模型对照组之间有显著性差异(P<0.01),并能保护血液系统功能。结论:杨梅多酚可保护小白鼠由核辐射引起的有形血细胞减少。 |
| 关 键 词： | 杨梅多酚 核 辐射 血液 小鼠 |
| 文章编号： | 1007-1237(2005)05-0391-02 |
| 收稿时间： | 2005-03-30 |
| 修稿时间： | 2005年3月30日 |
PROTECTIVE EFFECTS OF BAYBERRY POLYPHENOL ON MOUSE'S HEMATOLOGIC INJURY INDUCED BY NUCLEAR RADIATION |
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| TANG Pei-lian,CHI Wen,ZENG Hong-Hui.PROTECTIVE EFFECTS OF BAYBERRY POLYPHENOL ON MOUSE''''S HEMATOLOGIC INJURY INDUCED BY NUCLEAR RADIATION[J].Journal of Hainan Medical College,2005,11(5):391-392. | |
| Authors: | TANG Pei-lian CHI Wen ZENG Hong-Hui |
| Institution: | Out-patient Department, Guangdong college of pharmacy, Guangzhou 510224, P.R.China |
| Abstract: | Objective: To study the protective effects of Bayberry Polyphenol BPP on Mouse's hematologic injury by nuclear radiation in order to provide preclinical pharmacodynamic data for developing drug against nuclear radiation. Methods: The injured mouse model with decreasing tangible blood cells was induced by 60Co-r radiation. Results: BPP elevated tangible blood cell amount in the blood system and the difference between BPP and control group of pathological model was significant P<0.01. BPP showed protective effect on function of blood system. Conclusion: BPP could increase tangible blood cell induced by nuclear radiation. It is suggested that BPP could protect the function of blood system. |
| Keywords: | Bayberry Polyphenol nuclear radiation blood mouse |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |