丙泊酚与瑞芬太尼复合麻醉在无痛胃镜中的应用

目的:观察丙泊酚与瑞芬太尼复合麻醉在无痛胃镜检查中的临床效果。方法:ASAⅠ～Ⅲ级要求无痛胃镜检查的患者160例,随机分成丙泊酚组(P组)、丙泊酚复合瑞芬太尼组(PR组),每组80例,观察并记录检查前、检查中、检查后患者平均动脉压(MAP)、心率(HR)、血氧饱和度(SPO2)的变化和苏醒时间、离院时间及丙泊酚的用量。结果:P组检查中MAP、HR与术前及PR组比较差异有统计学意义(P<0.05),与P组比较,PR组苏醒、离院时间缩短(P<0.05),丙泊酚用量减少(P<0.05)。结论:丙泊酚复合瑞芬太尼用于无痛胃镜检查安全、可行,可减少丙泊酚的用量,有效降低呼吸抑制、体动等不良反应。

Effect of combination of propofol-remifentani on painless gastroscopy

Objective： To investigate efficiency and safety of propofol combined with remifentani in painless gastroscopy. Methods,. A total of 160 ASA Ⅰ-Ⅲ patients aged 26-70 years undergoing painless gastroscopy were randomly divided into propofol group （Group P） （n=80） and propofol remifentani group （GroupPR） （n=80）. The parameter, such as mean arterial pressure （MAP）, heart rate （HR）, Oxygen Saturation （SPO2）, dose of propofol, recovery time, discharged time were observed and recorded. Resuits： The changes of HR, MAP were less than the base line in group P during operation, and the differences were significant between two groups （P〈0.05）. While recovery time, discharged time and dose of propofol in group PR were significantly less （P 〈 0. 05 ）. Conclusions： Anesthesia with propofol and remifentani is safe for gastroscopy examination. Compund application of low dose remifentani can reduce the dose of propofol, side effect on respiratory depression and can shorten the recovery time .