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394例HIV抗体初筛阳性患者结果分析
引用本文:倪芳,刘雁雁,马蔡昀,吴志奇,徐华国,蒋理.394例HIV抗体初筛阳性患者结果分析[J].海南医学院学报,2014(12):1739-1741,1744.
作者姓名:倪芳  刘雁雁  马蔡昀  吴志奇  徐华国  蒋理
作者单位:南京医科大学第一附属医院检验学部
基金项目:中国高校医学期刊临床专项资金(11321435)~~
摘    要:目的:了解人类免疫缺陷病毒(HIV)抗体初筛阳性患者的流行病学特点,为区域性HIV筛查及防治工作提供依据。方法:选取2006年1月~2013年12月南京医科大学第一附属医院门诊及住院HIV抗体初筛结果为阳性的标本,送至江苏省疾控中心艾滋病(AIDS)确认实验室应用蛋白印迹法(WB)确认。结果:394例血清HIV抗体初筛结果为阳性,经WB复检,确认阳性214例,确认阴性167例,不确定13例。HIV抗体初筛阳性从2006年的9例增加到2013年的94例,其中确认阳性从5例增到49例。HIV抗体确认阳性以男性、20~49岁为主,主要分布在感染科、呼吸科、皮肤科、血液科和急诊科;而HIV抗体确认阴性者以女性、20岁以上为主,主要分布在血液科、产科、急诊科和生殖中心。结论:该地区HIV感染处在低水平,但HIV感染呈现上升趋势、存在以青年男性为主、科室分布广泛等特点。认识该特点,有利于相关部门开展区域性的HIV筛查及防治工作。

关 键 词:人类免疫缺陷病毒  抗体  艾滋病

Analysis of 394 HIV positive individuals by primary screening
NI Fang;LIU Yan-yan;MA Cai-yun;WU Zhi-qi;XU Hua-guo;JIANG Li.Analysis of 394 HIV positive individuals by primary screening[J].Journal of Hainan Medical College,2014(12):1739-1741,1744.
Authors:NI Fang;LIU Yan-yan;MA Cai-yun;WU Zhi-qi;XU Hua-guo;JIANG Li
Institution:NI Fang;LIU Yan-yan;MA Cai-yun;WU Zhi-qi;XU Hua-guo;JIANG Li;Department of Laboratory Medicine,the First Affiliated Hospital with Nanjing Medical University;
Abstract:Objective: To understand the epidemiological characteristics of patients with human immunodeficiency virus (HIV) antibody positive, and to provide the basis for HIV regional screening and prevention. Methods:The primary screening of serum HIV antibody form the inpatients or outpatients in the First Affiliated Hospital with Nanjing Medical University be- tween Jan 2006 and Dec 2013 were detected by enzyme-linked immuno sorbent assay. Serum with positive results was sent to provincial Centre of Disease and Control of further confirmation by Western Blotting test (WB). Results: Out of 394 cases with HIV positive in primary screening, including 214 confirmed with positive HIV, 167 with negative HIV and 13 cases with un- certainty. The numbers of positive HIV cases were increased from 9 in 2006 to 94 in 2013 in primary screening and were in- creased from 5 to 49 cases after confirmation by WB. The patients with confirmation of HIV positive were predominated by male aged 20-49 years old, who were mainly distributed in the Department of Respiration, Dermatology, Infection, Hematolo- gy and Emergency. Patients with confirmation of negative were predominated by female aged above 20, who were mainly distributed in the Department of Hematology, Obstetrics, Emergency and Reproductive Center. Conclusion: HIV infection is at low level in study area, but with an upward trend year by year, and characterized with majority of young male and wide distri- bution of departments. This study may helpful for regional HIV screening and prevention.
Keywords:HIV  Antibody  AIDS
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