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中药黄芪对肾病大鼠血浆蛋白血脂及肾血流动力学的影响
引用本文:樊淑玲,林善锬.中药黄芪对肾病大鼠血浆蛋白血脂及肾血流动力学的影响[J].上海医学,1998,21(3):146-147.
作者姓名:樊淑玲  林善锬
作者单位:上海医科大学附属华山医院肾病科
摘    要:探讨中药黄芪治疗肾病综合征的作用机制。方法,应用阿霉素静脉注射建立肾病大模型,同时给予黄芪干预治疗,三周后,观察其对血浆蛋白,血脂及肾血流动力学的影响。

关 键 词:肾病综合征  血流动力学  中医药疗法  黄芪  血脂

Effects of Chinese herbal medicine Astragalus on plasma protein lipidemia and renal hemodynamics in nephrotic rat
Fan Shuling,L in Shanyan Division of N ephrology,H uashan H ospital,Shanghai Medical University.Effects of Chinese herbal medicine Astragalus on plasma protein lipidemia and renal hemodynamics in nephrotic rat[J].Shanghai Medical Journal,1998,21(3):146-147.
Authors:Fan Shuling  L in Shanyan Division of N ephrology  H uashan H ospital  Shanghai Medical University
Institution:Fan Shuling,L in Shanyan Division of N ephrology,H uashan H ospital,Shanghai Medical University.Shanghai2 0 0 0 40
Abstract:Objective:To explore the mechanism of Chinese herbal medicine Astragalus in treatment of nephrotic syndrome.Method:Nephrotic ratmodel was made by tail vein injection of adriamycin 6 mg/ kg,3 weeks after,Astragalus was given,and changes of phasma protein lipidemia and renal hemodynamics were observed. Results:Itwas shown that plasma protein was significantly increased with significant decrease of lipidemia as compared with those of the normal controls.Clearance test showed thatthe glomerular filtration rate(GFR) and urinary sodium excretion(UNa V) were also significantly increased.Conclusion:The above effects might be the partial mechanism of Astragalus in treatment of nephrotic syndrome.
Keywords:Nephrotic syndrome    Astragalus treatment    Renal hemodynamics
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