| 帕金森病和多系统萎缩患者的肛门括约肌肌电图与自主神经功能障碍分析 |
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| 引用本文： | 张小瑾,傅毅,袁华强,吴逸雯,应薇娜,陈生弟.帕金森病和多系统萎缩患者的肛门括约肌肌电图与自主神经功能障碍分析[J].上海医学,2009,32(8). |
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| 作者姓名： | 张小瑾 傅毅 袁华强 吴逸雯 应薇娜 陈生弟 |
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| 作者单位： | 神经病学研究所,上海交通大学医学院附属瑞金医院神经内科,200025 |
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| 摘 要： | 目的 探讨肛门括约肌肌电图(EAS-EMG)在诊断帕金森病(PD)和多系统萎缩(MSA)中的作用.方法 对临床诊断的51例PD患者和42例MSA患者(拟诊MSA 33例、可能MSA 9例)进行EAS-EMG检查和自主神经功能障碍的临床特点分析,并评价EAS-EMG在MSA与PD鉴别中的判对率.结果 MSA患者的自发电位出现率(78.6%)、运动单位动作电位(MUP)平均时限(8.1±2.5)ms]和募集电位单纯相出现率(40.0%)均显著高于PD患者20.4%、(6.9±1.2)ms和12.2%,P值分别＜0.01、0.05].在MSA患者中,自主神经功能障碍累及范围越广,EAS-EMG自发电位出现率越高(Rs=0.505,P=0.001).以自发电位出现率和MUP平均时限为主要鉴别指标,EAS-EMG对PD和MSA预测的总体判对率为76.3%.结论 EAS-EMG检查结果 可作为鉴别MSA与PD的重要参考依据;MSA患者EAS-EMG检查异常与自主神经功能障碍存在一定的相关性.
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| 关 键 词： | 肛门括约肌肌电图 帕金森病 多系统萎缩 自主神经功能障碍 判对率 |
Analysis of external anal sphincter electromyography and autonomic nervous dysfunction in patients with Parkinson's disease and multiple system atrophy |
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| ZHANG Xiaojin,FU Yi,YUAN Huaqiang,WU Yiwen,YING Weing,CHEN Shengdi.Analysis of external anal sphincter electromyography and autonomic nervous dysfunction in patients with Parkinson''s disease and multiple system atrophy[J].Shanghai Medical Journal,2009,32(8). |
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| Authors: | ZHANG Xiaojin FU Yi YUAN Huaqiang WU Yiwen YING Weing CHEN Shengdi |
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| Institution: | ZHANG Xiaojin,FU Yi,YUAN Huaqiang,WU Yiwen,YING Weina,CHEN Shengdi.Department of Neurology,Institute of Neurology,Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China |
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| Abstract: | Objective To assess the value of external anal sphincter electromyography(EAS-EMG)in the differential diagnosis of Parkinson's disease(PD)and multiple system atrophy(MSA).Methods EAS-EMG was performed in 51 patients with PD and 42 patients who were diagnosed as having probably MSA(n=42)and possible MSA(n=9).The clinical features of autonomic nervous dysfunction were also recorded.The performance of EAS-EMG differential diagnosis between MSA and PD was evaluated.Results The occurance of spontaneous potential... |
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| Keywords: | External anal sphincter electromyography Parkinson's disease Multiple system atrophy Autonomic nervous dysfunction Predict correct percentage |
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