肝纤维化的CT、MR诊断初步探讨

目的　初步探讨CT、MR检查在肝纤维化临床诊断中的作用。方法　对 16 8例经肝穿刺活检病理检查证实的肝纤维化患者行CT和 /或MR检查 ,根据肝纤维化炎症活动度分级和纤维化程度分期进行影像资料和相关指标的统计分析。结果　肝左叶和脾脏的大小以及肝表面形态、门静脉侧支血管等的影像学改变 ,随着肝纤维化严重程度的加重而有统计学差异。结论　无创伤性的CT、MR检查是动态观察肝纤维化的病程演进和临床随访的有效手段。

Preliminary appraisal of diagnostic value of CT and MRI in hepatic fibrosis

Objective To appraise preliminarily the role of CT, MRI in clinical diagnosis of hepatic fibrosis. Methods CT and/or MRI were performed in 168 patients with hepatic fibrosis confirmed pathologically by liver biopsies. The imaging data and related parameters were statistically analyzed according to the grading of hepatic fibrosis and inflammatory activity, and the staging of hepatic fibrosis. Results The change of the size of the left lobe of the liver and the spleen, hepatic surface contours, collaterals of portal vein all increased as the severity of hepatic fibrosis enhanced, which were of statistical significance. Conclusion The non-invasive CT and MRI examinations are valuable tools for dynamic observations of hepatic fibrosis during its progression and clinical follow-up.