PCDH10基因甲基化与宫颈癌的研究进展 |
| |
引用本文: | 国宏莉,李江华,李斌,度长海,张丽.PCDH10基因甲基化与宫颈癌的研究进展[J].中国热带医学,2012,12(9):1151-1153. |
| |
作者姓名: | 国宏莉 李江华 李斌 度长海 张丽 |
| |
作者单位: | 1. 湖北医药学院附属人民医院,湖北十堰442000;湖北医药学院附属太和医院显微整形外科,湖北十堰442000 2. 湖北医药学院附属太和医院显微整形外科,湖北十堰,442000 3. 湖北医药学院附属人民医院,湖北十堰,442000 |
| |
基金项目: | 湖北十堰市科技攻关项目(No.ZD2011029) |
| |
摘 要: | PCDH10基因是原钙粘蛋白细胞粘附分子家族的成员之一,是一种重要的抑癌基因.DNA甲基化是抑癌基因失活的机制,PCDH10基因甲基化及其在子宫颈癌癌变中的作用机制还不清楚.现对宫颈癌中PCDH10基因甲基化的相关研究内容进行综述.
|
关 键 词: | PCDH10基因 DNA甲基化 宫颈癌 |
Research progress of PCDH10 methylation in cervical carcinoma |
| |
Institution: | GUO Hong-li, LI Jiang-hua, LI Bin, et al. (Dept of Pathology , Affiliated Hospital of HuBei Medical University, Shiyan 442000, Hubei,P. R. China) |
| |
Abstract: | PCDH10 gene is one of the members of the family of cadherin cell adhesion molecule,and it is one important anti-oncogene.DNA methylation is the mechanism of antioncogene inactivation.PCDH10 gene methylation and its role in cervical cancer are still unclear.In this paper,the related contents of methylation of PCDH10 gene in cervical cancer are reviewed. |
| |
Keywords: | PCDH10 DNA methylation Cervical carcinomas |
本文献已被 维普 万方数据 等数据库收录! |
|