宫颈疾病3 328例临床分析

目的探讨宫颈疾病发病情况及特点，为宫颈癌早诊早治提供依据。方法对2002年1月-2004年12月就诊的3328例宫颈疾病病人的临床资料进行回顾性分析。结果宫颈炎性病变占88％，宫颈上皮内瘤样变占7％，宫颈浸润癌占0．3％。HPV感染阳性632例，其中宫颈上皮内瘤样变HPV感染率为64％。宫颈浸润癌HPV感染率为90％。宫颈良性病变中HPV的阳性率明显低于宫颈上皮内瘤样变及宫颈癌患者（P〈0．01）。HPV感染的高峰年龄为18．28岁，宫颈癌及癌前病变的高峰年龄为30．48岁。高危HPV持续感染、多性伴、性传播疾病者是发病的高危因素。蛄论认真对待宫颈炎性病变，对HPV阳性者进行积极的跟踪、筛查是宫颈癌早期预防、诊治的重点。30—48岁是城市医院宫颈疾病诊治、宫颈癌防治的重点人群。

Clinical analysis of 3 328 patients with cervical illness

Objective To discuss the characteristics of cervical cancer and provide basis for early diagnosis of treatment. Methods The clinical data concerning 3 328 cervical cancer patients diagnosed from January 2001 to December 2004 were retrospectively analyzed. Results Cervical inflammation lesions were observed in 88% of the patients, CIN accounted for 7%, cervical evasive cancer 0.3%. 632 cases were infected with HPV of which benign cervical lesions accounted for 64% and cervical evasive cancer accounted for 90%. The positive rate for HPV in the patients with benign cervical lesions was obviously lower than that of the CIN (P<0.01). The peak infection of HPV occurred To the age groups of 18-28 years, while peak infection of cervical cancer was in the age group of 30-48 years. Continuous infection with HPV, multiple sexual partners and STD patients are the high risk factors. Conclusion Attention be paid to the early diagnosis and treatment of cervical cancer and measures be taken for management of the high risk age group.