直接进样碰撞池ICP-MS技术测定全血中二十种元素

目的建立直接进样八极杆碰撞池电感耦合等离子体质谱（ORS-ICP-MS）测定全血中二十种元素的快速测定方法。方法全血样用0．1％TritonX100＋0．1％HNO3稀释20倍后，用八极杆碰撞池电感耦合等离子体发射质谱法同时测定铅、砷、钒、镉等二十种元素含量。结果灵敏度高，各元素检出限在0．10μg/L-1．02μg/L之间；线性良好，线性相关系数均≥0．999；重现性好，变异系统RSD〈5％；准确度高，加标回收率在85．3％～112％之间，用冻干牛血铅、镉成分标准物质（GBW09139、GBW09140）、牛血成分分析标准物质（GBW（E）090062）作标样质控，分析结果与标准值吻合。结论建立方法简化了样品前处理过程，快速灵敏，精密度及准确度均符合要求，结果令人满意。

Direct determination of twenty elements in blood by octopole reaction system inductively coupled plasma mass spectrometry

Objective To establish the method for direct determination of 20 elements in blood by octopole reaction system inductively coupled plasma mass spectrometry (ORS-ICP-MS). Methods The samples were diluted by 0.1% Triton X-100+0.1%HNO3. The solution was directly analyzed by ORS-ICP-MS for determination of twenty elements, inclduign Pb,As,V,Cd etc. Results The detection limits of each element was between 0.005μg/L～1.09μg/L. Standard linear correlation r≥0.999. Standard deviations were below 5% ,recovery rates were in the range of 85.3%～112% .Standard reference materials were used as quality control standards and the analysis results conformed well to the certified values. Conclusion The method is simple, rapid, accurate and reliable for determination of samples.