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轻微认知功能损害的特点和老年记忆功能问卷的编制
引用本文:郭起浩,洪震,王蓓,吕传真.轻微认知功能损害的特点和老年记忆功能问卷的编制[J].中国行为医学科学,2003,12(6):675-677.
作者姓名:郭起浩  洪震  王蓓  吕传真
作者单位:复旦大学附属华山医院神经内科 上海200040 (郭起浩,洪震,王蓓),复旦大学附属华山医院神经内科 上海200040(吕传真)
摘    要:目的 分析轻微认知功能损害(MCI)的特点和编制老年记忆功能问卷。方法 选择符合MCI诊断标准的就诊者16例,年龄、性别和教育程度与MCI组匹配的极轻微认知功能损害(VMCI)和正常老人样本各16例,采用自行编制的老年记忆调查问卷、简易智能检查量表(MMSE)、韦氏记忆量表(WMS-RC)、听觉词语回忆测验(AVMT)等测验工具进行评定。结果 即刻记忆和总体智力在MCI、VMCI两组之间无显著差异,短时记忆、延迟回忆及长时记忆在两组之间有显著差异。老年记忆功能问卷主要由MCI、VMCI两组比较有显著差异的项目组成,总分20分。其总分与AVMT长延迟回忆有非常显著的相关性。以10分为划界分,老年记忆功能问卷对于检出MCI的敏感性和特异性优于WMS-RC总分和MMSE总分。结论 老年记忆功能问卷有助于快速有效地识别MCI。

关 键 词:轻微认知功能损害  老年记忆功能问卷  神经心理测验
文章编号:1005-8559(2003)06-675-03
修稿时间:2003年1月20日

Feature of mild cognitive impairment and establishment for brief screening questionnaire
GUO Qi-hao,HONG Zhen,WANG Bei,et al..Feature of mild cognitive impairment and establishment for brief screening questionnaire[J].Chinese Journal of Behavioral Medical Science,2003,12(6):675-677.
Authors:GUO Qi-hao  HONG Zhen  WANG Bei  
Institution:GUO Qi-hao,HONG Zhen,WANG Bei,et al. Dep. Neurology of Huashan Hospital,Fudan University,200040
Abstract:Objective To analyze feature of mild cognitive impairment(MCI) and establishment for elderly memory function questionnaire. Method Neuropsychological tests contained elderly memory function screening questionnaire, mini-mental state examination (MMSE), Wechsler memory scale-Chinese revised(WMS-RC),auditory verbal memory test (AVMT), Alzheimer disease assessment scale was examined in 16 patients with mild cognitive impairment(MCI), 16 very mild cognitive impairment(VMCI) and 16 normal controls matched age, sex and education. Result Short memory?delayed memory and remote memory rather than immediate memory and total intelligence were significantly difference between groups of MCI and of VMCI?Brief elderly memory function screening questionnaire contained 10 items of memory complaints. Its total score was significant correlative with long delayed memory of AVMT. Early detection of MCI by brief elderly memory function questionnaire better sensitivity and specificity than that of WMS-RC and MMSE, respectively? Conclusion Elderly memory function questionnaire contribute to identify MCI speedily and effectively.
Keywords:Mild cognitive impairment  Elderly memory function questionnaire  Neuropsychological tests
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