| 制订医学诊断参考值的混杂样本剖析法——Weibull分布在医学中的应用 |
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| 引用本文： | 王绍鑫.制订医学诊断参考值的混杂样本剖析法——Weibull分布在医学中的应用[J].贵阳医学院学报,1988(2). |
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| 作者姓名： | 王绍鑫 |
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| 作者单位： | 贵阳医学院卫生统计学教研室 |
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| 摘 要： | 本文以 Weibull 分布为数学模型,提出了:(1)以 Marquardt 非线性最小二乘法估计参数的剖析法;(2)一个系统的混杂样本剖析,参考值制订及相应假阴性率、漏诊率和误诊率估计的计算程序。通过剖析一临床资料,证实了本法的可靠性和可行性。
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| 关 键 词： | 参考值 混杂样本 Weibull 分布 数学模型 参数估计 |
A METHOD OF DISSECTING MIXED SAMPLES FOR ESTIMATING THE REFERENCE VALUES OF MEDICAL DIAGNOSIS |
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| Wang Shaoxin.A METHOD OF DISSECTING MIXED SAMPLES FOR ESTIMATING THE REFERENCE VALUES OF MEDICAL DIAGNOSIS[J].Journal of Guiyang Medical College,1988(2). |
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| Authors: | Wang Shaoxin |
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| Institution: | Wang Shaoxin Department of Health Statistics |
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| Abstract: | In this paper,we basing on the mathematical model of Weibull distribu- tions,present:(1).the Marquardt's nonlinear least square dissecting method; (2)a systematic computerized program for the dissection of mixed samples, the determination of reference values and the estimation of false-negative per- centages as well as the rate of mis-diagnosis and false-diagnosis.The results obtained from one clinical trial demonstrate that there is quite a agreement in the distribution and the reference values between the dissected and the control samples.The result is reliable and the method applicable in clinical practice. |
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| Keywords: | Reference values Mixed samples Weibull distribution Mathematical model Parameter estimation |
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