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血液灌流联合血液透析治疗终末期肾病肾性贫血的临床观察
引用本文:郑文博,刘吉国,晏佳.血液灌流联合血液透析治疗终末期肾病肾性贫血的临床观察[J].现代医学,2012,40(5):573-575.
作者姓名:郑文博  刘吉国  晏佳
作者单位:重庆市第三人民医院 肾内科,重庆,400014
摘    要:目的:观察血液灌流(HP)联合血液透析(HD)对慢性维持性HD患者终末期肾病(ESRD)肾性贫血的疗效.方法:选择我院维持性HD患者40例,随机分为治疗组(HD联合HP)和对照组(仅行HD)各20例,在疗程化治疗前后比较血常规、超敏C反应蛋白(hs-CRP)和全段甲状旁腺素(i-PTH)的变化.结果:治疗组病人血红蛋白(Hb)、血细胞比容(Hct)、血清铁蛋白(SF)升高较对照组更明显(P<0.05),hs-CRP、i-PTH清除效果好于HD组(P<0.05).结论:HP联合HD能更好地纠正ESRD患者的贫血状况.

关 键 词:血液透析  血液灌流  肾性贫血

Observation of hemoperfusion combined with hemodialysis treatment on renal anemia
ZHENG Wen-bo , LIU Ji-guo , YAN Jia.Observation of hemoperfusion combined with hemodialysis treatment on renal anemia[J].Modern Medical JOurnal,2012,40(5):573-575.
Authors:ZHENG Wen-bo  LIU Ji-guo  YAN Jia
Institution:(Department of Nephrology,the Third People’s Hospital of Chongqing,Chongqing 400014,China)
Abstract:Objective: To observe the effectiveness of treatment on end-stage renal disease anemia with hemoperfusion(HP) combined with hemodialysis(HD).Methods: 40 maintenance hemodialysis patients were selected,and divided into treatment group(HD+HP group,n=20) and control group(HD group,n=20) randomly.Blood routine index,C-reactive protein(hs-CRP) and intact-phenylthiohydantoin(i-PTH)were measured and compared before and after course of treatment.Results: The levels of hemoglobin(Hb),hemotocrit(Hct),serum ferritin(SF)in HD+HP group were significantly higher than that HD group(P<0.05),hs-CRP and i-PTH were cleared away better in HD+HP group,and the difference was significant(P<0.05).Conclusion: HP combined with HD ameliorates the anemia in ESRD patients more effectively.
Keywords:hemodialysis  hemoperfusion  renal anemia
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