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经皮穿刺氩氦刀冷冻与肝动脉栓塞化疗联合应用治疗肝脏恶性肿瘤
引用本文:方文,滕皋军,何仕成,邓刚,郭金和,朱光宇,李国昭.经皮穿刺氩氦刀冷冻与肝动脉栓塞化疗联合应用治疗肝脏恶性肿瘤[J].现代医学,2004,32(6):382-385.
作者姓名:方文  滕皋军  何仕成  邓刚  郭金和  朱光宇  李国昭
作者单位:东南大学附属中大医院,放射科,江苏,南京,210009
摘    要:目的 探讨经皮穿刺氩氦刀冷冻对已行肝动脉栓塞化疗 (TACE)的肝脏恶性肿瘤患者的可行性、安全性及有效性。方法  7例已行TACE的肝脏恶性肿瘤患者中 6例为原发性肝癌 ,1例为转移性肝肿瘤。CT导向下采用Seldinger法置入 11F自制标记导管鞘 ,用 3mm氩氦刀行经皮穿刺冷冻治疗。结果  7例 (10个病灶 )穿刺及冷冻均获得成功 ,无严重并发症发生。平均随访时间 7.5个月 ,部分缓解 (PR) 4例 ,无变化 (NC) 2例 ,进展 (PD) 1例。结论 经皮穿刺氩氦刀冷冻与TACE联合应用对肝脏恶性肿瘤是一种安全有效的治疗方法 ,二者联合应用可弥补两种疗法可能存在的不足。

关 键 词:肝脏肿瘤  恶性  冷冻外科  氩氦刀  经皮穿刺  化学栓塞术
文章编号:1671-7562(2004)06-0382-04
修稿时间:2004年6月14日

Percutaneous cryoablation combined with TACE for liver carcinoma
FANG Wen,TENG Gao-jun,HE Shi-cheng,DENG Gang,GUO Jin-he,ZHU Guang-yu,LI Guo-zhao.Percutaneous cryoablation combined with TACE for liver carcinoma[J].Modern Medical JOurnal,2004,32(6):382-385.
Authors:FANG Wen  TENG Gao-jun  HE Shi-cheng  DENG Gang  GUO Jin-he  ZHU Guang-yu  LI Guo-zhao
Abstract:Objective To explore the feasibility, effectiveness and safety of percutaneous cryoablation combined with transcatheter arterial chemoembolization (TACE) in the treatment of liver carcinoma. Methods Percutaneous cryoablation was performed in 7 patients(6 primary liver cancer and 1 metastatic liver cancer), which were treated with preoperational TACE. With CT guidance, 11-F catheter sheath and 3-mm cryosurgery system were employed.Results The therapy was successfully performed in 7 patients ( 10 regions). No serious complications occurred. The average follow up was 7.5 months, and PR 4 cases, NR 2 cases, PD 1 case. Conclusions Percutaneous cryoablation for liver carcinoma after TACE is safe and effective,it may be a useful supplement for each method alone.
Keywords:liver carcinoma  cryosurgery  cryocare system  percutaneous  chemoembolization
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