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西安市一起新型冠状病毒肺炎家族聚集性疫情调查分析
引用本文:白尧,陈志军,宋姝璇,贺真,陈保忠,邵中军,刘昆.西安市一起新型冠状病毒肺炎家族聚集性疫情调查分析[J].山东大学学报(医学版),2020,58(10):95-99.
作者姓名:白尧  陈志军  宋姝璇  贺真  陈保忠  邵中军  刘昆
作者单位:1. 西安市疾病预防控制中心, 陕西 西安 710054;2. 空军军医大学军事预防医学系军队防疫与流行病学教研室, 陕西 西安 710032
基金项目:国家自然科学基金(81803289);军事医学创新工程基金(18CXZ011)
摘    要:目的 调查分析西安市一起新型冠状病毒肺炎(COVID-19)家族聚集性疫情传播特征,为制定防控策略提供科学依据。 方法 对COVID-19确诊病例、无症状感染者及密切接触者进行流行病学调查,分析疫情的传播链,采集病例及相关人员的鼻咽拭子标本进行SARS-CoV-2核酸检测。 结果 本次疫情累计发现4例普通型、1例危重症型确诊病例和2例无症状感染者,危重症病例最终死亡。首例病例A于2020年1月31日发病,其他病例在首例病例发病后的1~13 d内发病,病例B、C和D、E分别为二、三、四代病例。 结论 家族聚集性疫情是COVID-19的防控重点,及早发现传染源,对密切接触者进行筛查隔离,防止传播扩散有重要意义。

关 键 词:新型冠状病毒肺炎  聚集性疫情  传播特征  

Investigation of a family cluster outbreak of coronavirus disease 2019 in Xian
BAI Yao,CHEN Zhijun,SONG Shuxuan,HE Zhen,CHEN Baozhong,SHAO Zhongjun,LIU Kun.Investigation of a family cluster outbreak of coronavirus disease 2019 in Xian[J].Journal of Shandong University:Health Sciences,2020,58(10):95-99.
Authors:BAI Yao  CHEN Zhijun  SONG Shuxuan  HE Zhen  CHEN Baozhong  SHAO Zhongjun  LIU Kun
Institution:1. Institute for Infectious Diseases Prevention, Xian Center for Disease Prevention and Control, Xian 710054, Shaanxi, China;2. Department of Epidemiology, School of Public Health, Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Air Force Medical University, Xian 710032, Shaanxi, China
Abstract:Objective To investigate the transmission characteristics of a family cluster outbreak of coronavirus disease 2019(COVID-19)in Xian, in order to provide reference for prevention and control efforts. Methods Epidemiological investigations on the confirmed cases, asymptomatic carriers and their close contacts were carried out, the transmission chain was analyzed, and the pharyngeal swabs for nucleic acid tests of SARS-CoV-2 were collected. Results A total of 4 mild cases, 1 severe case and 2 asymptomatic carriers were tracked. The severe case finally died. The first case(A)had onset on Jan. 31, 2020, and the other cases(B, C as well as D, E)had onset 1-13 days later, who were second, third, and fourth generation cases. Conclusion The prevention and control of COVID-19 should focus on family cluster outbreak. Early detection of the source of infection and screening and isolation of close contacts are important to prevent the spread of the epidemic.
Keywords:Coronavirus disease 2019  Cluster outbreak  Transmission characteristics  
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