骨关节炎患者髌软骨MRI T2图的临床评价

目的比较髌骨关节炎患者按照K L分级分组和按照体质量指数(BMI)分组时髌软骨横向弛豫时间(T2值)的应用价值。方法72例患者按照K L分为正常、轻度和重度骨关节炎（OA）组；按照BMI分为正常、超重和肥胖三组，髌软骨用横断面四回波SE序列扫描，测量髌软骨T2值并进行统计学分析。结果正常组、轻度组和重度组骨关节炎患者T2值分别为（37.9±4.9）、（48.5±7.5）、（51.7±5.2）ms，轻度和重度组间差别无统计学意义（P＞0.05），BMI对髌软骨的T2值有明显的影响（P＜0.001），三组间差异均有统计学意义（P均＜0.05）。结论按照骨关节炎K L分级时T2值变化不敏感；按照BMI分组时,T2值的差别反映了髌股关节炎时髌软骨结构成分改变程度，提示BMI可能是引起T2值增加的潜在因素。

MRI T2-mapping of patellar cartilage in patients with osteoarthritis

To explore the T2 value of patellar cartilage grouped respectively by radiographic stage of patello femoral OA and by body mass index(BMI). Methods72 subjects were grouped based on K L into the normal, mild OA, and severe OA groups and on BMI into the normal, over weight, and obese groups. They were scanned using four echoes′ spine echo, and the T2 value of patellar cartilage was measured. ResultsThe mean T2 value was 37.9±4.9 ms, 48.5 ±7.5 ms, and 51.7±5.2 ms in the normal group, mild OA group, and severe OA group. No significance was found between the mild and severe OA groups(P＞0.05). BMI had a significant effect on T2 value (P＜0.001, and P＜0.05 among the three groups). ConclusionResults indicate that the T2 values are not sensitive to changes according to radiographic stages of OA. T2 values with BMI signify structural changes of patellar cartilage, and BMI may be a potential factor for an increase of T2 values.