| 人胚胎肝脏红系造血的亚显微结构 |
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| 引用本文： | 潘祥麟,张茂宏,李少玲,范博逊,张琪.人胚胎肝脏红系造血的亚显微结构[J].山东大学学报(医学版),1988(4). |
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| 作者姓名： | 潘祥麟 张茂宏 李少玲 范博逊 张琪 |
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| 作者单位： | 山东医科大学附属医院内科，山东医科大学附属医院内科，山东医科大学郓城县人胚胎造血功能研究组，山东医科大学电子显微镜中心实验室，山东医科大学电子显微镜中心实验室，电山东医科大学子显微镜中心实验室 |
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| 摘 要： | 用透射电镜对10例3～9个月胎龄的人胚胎肝脏红系造血进行了观察。发现胚胎期肝脏红系造血主要发生在肝实质组织内;3～6个月胎龄的胚胎肝脏中红系造血活跃,9个月胎龄者红系造血仍存在,但造血细胞呈局灶性分布,胚胎肝脏产生的幼红细胞在亚显微水平与正常人骨髓产生的幼红细胞无明显差异;胚胎肝细胞有适应红细胞系造血的亚显微结构,提示在胚胎一定时期内肝实质组织是有利红系细胞分化发育的微环境;胚胎期肝窦内皮细胞的不连续性和出现幼红细胞,提示造血过程中不能像骨髓那样有效地控制血细胞的释放。
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| 关 键 词： | 造血系统 红细胞生成 肝 胚胎 显微镜检查 电子 |
ULTRASTRUCTURE OF THE HEPATIC ERYTHROPOIESIS IN HUMAN FETUSES |
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| Pan Xianglin et al Dept.of.Inter.Med.of Affiliated Hospital,Shandong Medical University.ULTRASTRUCTURE OF THE HEPATIC ERYTHROPOIESIS IN HUMAN FETUSES[J].Journal of Shandong University:Health Sciences,1988(4). |
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| Authors: | Pan Xianglin DeptofInterMedof Affiliated Hospital Shandong Medical University |
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| Abstract: | The hepatic erythropoiesis in human fetuses was studied
with transmission electron microscope in the livers of 10 human embryos
obtained by artificial abortion.Their gestational age ranged from 3 mon-
ths to 9 months(a case of anencephaly).The crythropoiesis in parenc-
hymal tissue of the livers was observed.The ultrastructure of the fetal
hepatic cells in various phases was discribed.The ultrastructurc of the
erythroblasts in various stages of development was mentioned.It was found
that there is no remarkabal ultrastructural difference between the crythro-
blasts of the fetal liver and those of the adult bone marrow,The rela-
tionship between erythropoiesis of the fetal liver and the development of
the fetal hepatic cells was discussed.It was considered that ultrastructural
change of fetal hepatic cells is adapted to the differentiation and develop-
ment of the cells of the erythrocytic line in the fetal liver. |
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| Keywords: | Hematopoietic system Erythropoiesis Liver Embryo Microscopy electron |
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