阻塞性睡眠呼吸暂停与脑卒中关系的研究

阻塞性睡眠呼吸暂停综合征(OSAS)对心血管的影响因素,涉及到神经、体液、血管和炎症异常。目前,研究认为,OSAS引起的血流动力学、血管、炎症、血凝、氧化应激改变,都是可能的脑血管疾病的危险因素。而且,OSAS可以造成全身多器官损害,更认识到OSAS是脑卒中的独立危险因素,可以造成脑功能损害。OSAS能够增加缺血性脑卒中患者长期的病死率,但OSAS与脑卒中相互影响的具体机制,尚有待阐明。

Study on the Relationship Between Strock and Obstructive Sleep Apnea Syndrome

It has been confirmed that obstructive sleep apnea syndrome（OSAS） could cause multiple changes of vascular endothelium,inflammation,mechanisms of coagulation,oxidative stress and other links.In addition,Study rusults confirmed that OSAS might cause an injury of multisystem and organ,an independent risk factor of strock,an injury of neurological function and an increase of mortalityin patients with ischemic stroke.However,it remains to be elucidated that the detailed mechanisms of interrelationship between OSAS and strock.