消痔灵注射液肾动脉栓塞的实验研究

本实验利用消痔录注射液（代号“775”）栓塞兔肾动脉,使肾脏梗死,将实验动物分四组,分别注入纯“775”,50%“775”碘油混合液,75%“775”碘油混合液,纯碘油,各组动物分别于术后3天、7天、3周经平片,IVP,腹主动脉造影追踪观察,3周后全部动物处死送病理检查,结果表明：B组栓塞效果优于其他组,且易操作和观察,并对其栓塞机制及毒性进行了讨论。

Experimental Study of Transcatheter Renal Arteral Embolization with Xiaozhiling Injection

The renal arteries of twenty one rabbits were embolized by Xiaozhiling Injection (code"775")to infarct their kidneys. According to the embolic agents given,the experimental animals were divided into the following 4 groups: "775"(A), 50% "775" --Lipiodol Mixture (B), 75% "775"--Lipiodol mixture (C) and Lipiodol (D),Plain abdominal radiograph, IVP and abdominal arterial angiography were per- formed 3 days, 7 days and 3 weeks after embolization respectively. All experimental animals were killed after 3 weeks and examined pathologically. The results show that the embolizing effect in group B is superior to the others,and it is easy to manipulate and observe also. The mechanism of emboliza- tion and toxicitv of the agent have been discussed,