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野桃树根对肝癌细胞毒作用的实验研究
引用本文:祝金泉,黄德强,等.野桃树根对肝癌细胞毒作用的实验研究[J].江西医学院学报,2001,41(4):17-19.
作者姓名:祝金泉  黄德强
作者单位:[1]江西医学院第一附属医院消化内科研究所,江西南昌330006 [2]江西医学院第一附属医院消化内科研究所,江西南昌33
摘    要:目的:探讨野桃树根对肝癌细胞毒作用。方法:肝癌细胞株与野桃树根浸出液共同体外培养,MTT法测细胞毒作用。结果:0.2%,0.1%,0.05%,0.025%浓度的野桃树根浸出液对SMMC7721细胞的抑制率分别为77.97%,64.06%,36.34%,33.75%;0.2%,0.1%,0.05%,0.025%,0.0125%浓度的野桃树根浸出液对SK-HEP-1细胞的抑制率分别为100%,100%,100%,88.98%,82.64%。结论:野桃树根浸出液在体外对肝癌细胞有较强的杀伤作用。

关 键 词:野桃树根  细胞毒  肝肿瘤  体外实验
文章编号:1000-2294(2001)04-0017-03
修稿时间:2001年3月6日

Experimental Study of Cytotoxicity on Hepatocarcinoma with Root of wild Peach Tree
Abstract:Objectives:To study cytotoxicity on hepatocarcinoma with Root of Wild Peach Tree. Method: SMMC7721 and SK HEP 1 the hepatocarcinomas Ascitic carcinoma cell lines were cultured in vitro with 1640 medium contained Root of wild peach tree. The cytotoxicity was tested by MTT method. Result: Inhibition Rate(IR) of the drug 0.2%, 0.1%, 0.05%, 0.025% to AMMC7721 were 77.97%, 64.06%, 36.34%, 33.75%, respectively; IR of the drug 0.2%, 0.1%, 0.05%, 0.025%, 0.0125% to SK HEP 1 were 100%, 00%, 100%, 88.98%, 82.64% respectively. Conclusions: These results indicate that Root of wild peach Tree can significantly suppress SMMC7721 and SK HEP 1 cells in vitro.
Keywords:Hepatocarcinoma  Root of wild peach Tree  Cytotoxicity    
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