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肝移植术后对肠道黏膜SIgA分泌的影响及意义
引用本文:郑凤娇,罗显荣,刘树人.肝移植术后对肠道黏膜SIgA分泌的影响及意义[J].华南国防医学杂志,2011,25(2):122-123.
作者姓名:郑凤娇  罗显荣  刘树人
作者单位:解放军458医院检验科,广东广州,510602
基金项目:总后卫生部"十一五"专项基金项目
摘    要:目的 观察肝移植前后,肠道黏膜分泌型免疫球蛋白(secretory immunoglobulin A,SIgA)分泌变化情况,为临床施行肝移植术后胃肠道功能的恢复提供依据.方法 选取20例肝脏病变行肝移植的患者和20例体格检查健康者作为研究对象,检测患者肝移植术前后和健康体检者粪便内的SIgA含量.结果 肝移植患者肝移...

关 键 词:肝硬化  肝移植  分泌型免疫球蛋白  肠道黏膜免疫

Effects of Liver Transplantation on Secretion of SIgA in Intestinal Mucosa
ZHENG Feng-jiao,LUO Xian-rong,LIU Shu-ren.Effects of Liver Transplantation on Secretion of SIgA in Intestinal Mucosa[J].Military Medical Journal of South China,2011,25(2):122-123.
Authors:ZHENG Feng-jiao  LUO Xian-rong  LIU Shu-ren
Institution:.Department of Clinical Laboratory,No.458 Hospital of the People’s Liberation Army,Guangzhou Guangdong 510602,China
Abstract:Objective To observe the changes of secretory immunoglobulin A(SIgA) in intestinal mucosa of patients before and after liver transplantation,and supply reference for the recovery of gastrointestinal immune function after liver transplantation.Methods SIgA in the dejecta of 20 healthy subjects and 20 patients before and after liver transplantation were detected and analysed.Results Before liver transplantation,SIgA contents in patients were lower than healthy subjects.After liver transplantation,SIgA contents increased gradually and arrived at the normal level.Conclusion Hepatocirrhosis can restrain the secretion of SIgA.After the liver transplantation,SIgA in the gastrointestinal mucosa can return to normal level gradually and the gastrointestinal immune function is obviously recovered.
Keywords:Hepatocirrhosis  Liver transplantion  Secretory immunoglobulin A  Intestinal mucosal immunity
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