临床药师参与镇痛药物治疗对晚期肿瘤患者疼痛疗效的影响

目的：探讨临床药师参与镇痛药物治疗工作后，对晚期肿瘤患者疼痛治疗效果的影响。方法：收集重度癌痛患者30例，比较临床药师参与止痛治疗3周前后的治疗效果、不良反应及治疗成本间的差异，并进行成本效益分析。结果：药师参与癌痛治疗前后最严重最痛时评分分别为8.27、6.47，差异比较有统计学意义（P〈0.05）；爆发痛次数分别为4.63、2.96，差异比较有统计学意义（P〈0.05）、服药后止痛药物持续起效时间（NRS≤4）分别为4.58、8.46，差异比较有统计学意义（P〈0.05）；总缓解率分别为：46.67%、86.67%，差异比较有统计学意义（P〈0.05）；在不良反应方面比较没有差异；治疗成本方面药师参与后费用较参与前高，但成本效益分析发现，药师参与后患者获益率较高。结论：临床药师在参与晚期肿瘤患者的疼痛治疗后，在不良反应没有增加的情况下，患者的止痛效果明显提高，临床获益率提高。

Clinical pharmacists involved in analgesic treatment on the efficacy of pain in patients with advanced cancer

To investigate the clinical pharmacists involved in analgesic medications work , treatment of pain in patients with advanced cancer effects . Methods： 30 patients with severe cancer pain , more clinical pharmacists involved in pain treatment difference after three weeks of treatment effects , adverse reactions and treatment costs between cost and benefit analysis . Results：The participation of pharmacists before and after treatment of the most severe pain most pain scores were 8 . 27 , 6 . 47 , the difference was statistically significant（P〈0 . 05）; breakthrough pain were 4 . 63 , 2 . 96 times , the difference was statistically significant（P〈0 . 05）, after taking pain medications continue onset time（NRS≤4） were 4 . 58 , 8 . 46 , the difference was statistically significant （P〈0 . 05）;overall response rates were： 46 . 67%, 86 . 67%, comparing statistical difference significance （P〈0 . 05）;relatively no difference in adverse reactions ; front costs involved in treatment costs compared with pharmacists participating in high , but the cost-benefit analysis found that the pharmacists involved in a high rate of patient benefit . Conclusion： The clinical pharmacists to participate in the treatment of pain in patients with advanced cancer , no increase in adverse circumstances , the analgesic effect in patients with significantly improved clinical benefit rate .