七氟烷与丙泊酚在麻醉苏醒期躁动发生率的临床研究

目的:比较丙泊酚、七氟烷复合芬太尼全身麻醉苏醒期躁动的发生情况。方法:120例ASAⅠ～Ⅱ级择期全身麻醉下行胆囊切除术的患者。随机分成两组:丙泊酚组、七氟烷组。观察各组苏醒期躁动发生率和睁眼时间、拔管时间,监测躁动发生前后血压、心率及脉搏血氧饱和度。结果:七氟烷组苏醒期躁动发生率分别为16.67%,高于丙泊酚组的1.67%(P<0.05);睁眼时间、拔管时间差异不具有显著性意义(P>0.05);躁动发生前后血压、脉搏血氧饱和度差异无显著性意义(P>0.05),而心率在躁动发生后明显增快(P<0.05)。结论:七氟烷吸入麻醉苏醒期躁动发生率明显高于丙泊酚全身麻醉。

Emergence Agitation after Total Introvenus or Inhalation Anesthesia for Maintenance with Fentanil

Objective：To evaluate the effect of propofol and sevoflorane on emergence agitation.Methods：120 patients scheduled for radical operation of cholecystectomy were enrolled in this prospective study and randomly divided into two groups.Patients were randomly assigned to receive fentanil with sevoflurane or propofol anesthesia for maintenance.We compared the incidence of emergence agitation,eyes open time,extubation time,and BP,HR,SpO2 during emergence agitation.Results：Patients who received sevoflorane suffered more incidence than propofol（16.67% VS 1.67%）.Opens eye time and extubation time were showed no significant variance among two groups.After restlessness,BP and SpO2 didn＇t vary significantly compared to pre-agitation values,while HR increased significantly associated with restlessness.Conclusion：The association of propofol and fentanil for anesthesia maintenance resulted in a lower incidence of postoperative agitation compared with the association of sevoflurane and fentanil.