| 对IgM肾病的探讨 |
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| 引用本文： | 任青,周希静,杨玉秀,冯江敏,周惠英.对IgM肾病的探讨[J].中国医科大学学报,1986(3). |
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| 作者姓名： | 任青 周希静 杨玉秀 冯江敏 周惠英 |
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| 作者单位： | 中国医科大学附属第一医院泌尿内科，中国医科大学附属第一医院泌尿内科，中国医科大学附属第一医院泌尿内科，中国医科大学附属第一医院泌尿内科，中国医科大学 |
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| 摘 要： | 50例肾活检的原发性肾小球肾炎中,发现6例IgM肾病。主要病理特点为系膜增殖及IgM荧光沉积。临床表现以肾病综合征为特点,血清IgM升高,蛋白尿及血尿,并呈高凝状态。
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| 关 键 词： | IgM肾病 肾活检 肾病综合征 高凝状态 |
RESEARCH FOR IgM NEPHROPATHY |
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| Reng Qin,et al Dept. of Internal medicine,First Affiliated Hospital.RESEARCH FOR IgM NEPHROPATHY[J].Journal of China Medical University,1986(3). |
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| Authors: | Reng Qin Dept of Internal medicine First Affiliated Hospital |
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| Abstract: | In a serics of 50 renal biopsy specimens, 6 patients with primary glomerulo-nephritis showed IgM as the main glomerular immunefluorescence findirg. Bylightmicroscopy, 1 of these specimens showed minimal charge, 2 showed mild mesan-gial hypercellulority and 3 showed fecal segmenta glomerulosclerosis. Electronicmicroscopy showed mesangial hypercellularity, mesangial electrondense depesitsand fusion of epithelial foot proceesses. These 6 patients all had nephroticsyndreme and 5 of 6 had hematuria. The mean serum IgM level was significantlyhigher than that in healthy control and 5 had positive of urinary FDP, 2 patients had extremity vein thrombosis. It proved that the coagulation and fibrinolysistake part in the link of onset.Our results suggest that there is a primary glo-merulonephritis characterized by glomerular fluorescent IgM deposit, high serumconcentration of IgM, heterogenous clinical pictures and renal histology rangingfrom minimal change to mild mesangial-cell proliferation and focal glome-rulosclerosis |
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| Keywords: | IgM nephtopathy Biopsy Nephrotic syndrome Hyrercoagula-tion State |
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