| 原因不明性肝炎血清TTV DNA的检出和意义 |
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| 引用本文： | 舒波,窦晓光,刘沛.原因不明性肝炎血清TTV DNA的检出和意义[J].中国医科大学学报,1999,28(5):362-363. |
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| 作者姓名： | 舒波 窦晓光 刘沛 |
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| 作者单位： | 中国医科大学第二临床学院传染科!沈阳110003(舒波，窦晓光，刘沛，王兆荃)，解放军第202医院(黄敦武) |
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| 摘 要： | 目的：调查原因不明性肝炎的ＴＴＶ感染状况。方法：设计ＴＴＶ基因的特异性引物，应用ＰＣＲ反应检测４８ 例原因不明性肝炎血清中的ＴＴＶ ＤＮＡ。结果：４８例原因不明性肝炎中１３ 例ＴＴＶ ＤＮＡ阳性（２７．１％ ），其中急性肝炎９ 例，慢性肝炎３ 例，亚急性重型肝炎１例。结论：ＴＴＶ感染是原因不明性肝炎的致病因子，ＴＴＶ 感染能引起急性、慢性以及重型肝炎
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| 关 键 词： | 输血传播病毒 DNA 聚合酶链式反应 原因不明性肝炎 |
Detection of TTV Infection and Clinical Investigation in Patients with Hepatitis of Unknown Etiology |
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| Shu Bo,Dou Xiaoguang,Liu Pei,et al.Detection of TTV Infection and Clinical Investigation in Patients with Hepatitis of Unknown Etiology[J].Journal of China Medical University,1999,28(5):362-363. |
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| Authors: | Shu Bo Dou Xiaoguang Liu Pei |
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| Abstract: | Objective: We investigated investigate the presence of TTV infection among patients with hepatitis of unknown etiology. Methods: Forty eight serum samples from patients with hepatitis of unknown etiology were detected for TTV DNA by PCR methods. Results: The positive rate of TTV DNA accounted for 27.1% (13/48) in patients with hepatitis of unknown etiology. Among 13 patients with TTV DNA positive response, 7 were acute hepatitis, 5 were chronic hepatitis and 1 was subfulminant hepatitis. Conclusion: TTV infection could be associated with occurence of hepatitis, and could result in acute, chronic and fulminant hepatitis. |
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| Keywords: | TTV infection PCR hepatitis of unknown etiology |
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