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不同金属烤瓷冠对龈沟液内肿瘤坏死因子-α水平的影响
引用本文:卓锋,汲平.不同金属烤瓷冠对龈沟液内肿瘤坏死因子-α水平的影响[J].泰山医学院学报,2008,29(1):19-21.
作者姓名:卓锋  汲平
作者单位:山东大学口腔医学院修复科,山东,济南,250012
摘    要:目的通过对不同材料的烤瓷冠修复后龈沟液(gingival crevicular fluid,GCF)内肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)水平的测定,探讨内冠材料对牙周的影响。方法选择临床病例24例,采用镍铬合金烤瓷冠和金铂合金烤瓷冠修复,分别在修复前、修复后6个月进行临床检查和取GCF,进行GCF量和TNF-α水平的测定。结果6个月时镍铬合金组与金铂合金组在指标上均有明显差异。结论非贵金属对牙周组织有不利影响。

关 键 词:烤瓷熔附金属全冠  龈沟液  肿瘤坏死因子
文章编号:1004-7115(2008)01-0019-03
修稿时间:2007年10月11

Effect of different PFM materials on the level of TNF-α in gingival crevicular fluid
ZHUO Feng,JI Ping.Effect of different PFM materials on the level of TNF-α in gingival crevicular fluid[J].Journal of Taishan Medical College,2008,29(1):19-21.
Authors:ZHUO Feng  JI Ping
Institution:(Dept. of Prosthodontics, School of Stomatology, Shandong University, Jinan 250012 ,China)
Abstract:Objective: To investigate the effect of different inner crown materials on periodontal tissue by means of measuring the level of TNFα in gingival crevicular fluid(GCF) after PFM restoration.Methods: The anterior teeth of 24 patients selected by random were restored by Ni-Cr alloy PFM and Au-Pt alloy PFM.GCF was collected from labial and lingual of mesial site and distal site before the tooth preparation by filter paper.At the point of 6 month after cementation,GCF was collected at the same sites.The level of TNF-α was detected by enzyme-linked-immunoadsorbent assay(ELISA)method,and analyzed the variation between the pre-restoration and post-restoration.Results: Compared with pre-restoration,all indexes had significant difference between the Ni-Cr alloy group and the Au-Pt alloy group after 6 month.Conclusion: Non-noble metal has bad effect on the peirodontal tissue.
Keywords:porcelain-fused-to-metal(PFM)  gingival crevicular fluid(GCF)  tumor necrosis factor(TNF)
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