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玉米须多糖的利尿作用研究
引用本文:窦传斌,杜娟,许启泰.玉米须多糖的利尿作用研究[J].河南大学学报(医学版),2007,26(3):35-37.
作者姓名:窦传斌  杜娟  许启泰
作者单位:1. 河南省医药学校,河南,开封,475001
2. 河南大学药学院,河南,开封,475001
摘    要:目的:研究玉米须多糖(SMPS)的利尿作用。方法:采用代谢笼法和滤纸法测定NS负荷大、小鼠的排尿量及尿中Na+、K+、Cl-的含量.采用甘油致大鼠肾衰竭模型观察SMPS对肾衰竭大鼠排尿的影响。结果:高、中剂量的SMPS可明显增加大、小鼠的排尿量,增加尿液中K+、Cl-的含量,对Na+含量无明显影响;增肾衰竭大鼠的排尿量。结论:玉米须多糖具有明显的利尿作用。

关 键 词:玉米须多糖  利尿作用  药理作用
文章编号:1672-7606(2007)03-0035-03
修稿时间:2007-05-21

Study on diuretic effect of stigma maydis polysaccharide
DOU Chuan-bin,DU Juan,XU Qi-tai.Study on diuretic effect of stigma maydis polysaccharide[J].Journal of Henan University,2007,26(3):35-37.
Authors:DOU Chuan-bin  DU Juan  XU Qi-tai
Institution:1. Henan Pharmaceutical School, Henan Kaifeng 475001, China; 2. Pharmaceutical College of Henan University, Henan Kaifeng 475001, China
Abstract:Objective: To observe the antipyretic and diuretic effect of Stigma Maydis Polysaccharide(SMPS) Methods: The urinary output of the loading rats and mice with NS and the contents of Na+、K+、Cl-in the rats′urine was tested;the model of acute renal failure was established by injecting glycerol.Results: SMPS at the doses of 2 g/ kg and 1g/ kg could significantly increase the urinary output of the loading rats and mice with NS,and the contents of K+、Cl-in the rats′urine and the content of Na+remained unchanged.Conclusion: SMPS manifests considerable diuretic effect.
Keywords:Stigma Maydis Polysaccharide(SMPS)  diuretic effect  pharmacological study
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