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玉蜀黍苞叶和玉米棒提取物α-糖苷酶抑制活性
引用本文:尹震花,顾雪竹,顾海鹏,康文艺.玉蜀黍苞叶和玉米棒提取物α-糖苷酶抑制活性[J].河南大学学报(医学版),2012(2):88-90.
作者姓名:尹震花  顾雪竹  顾海鹏  康文艺
作者单位:河南大学中药研究所;中国中医研究院中药研究所
基金项目:河南省科技厅重点项目(102102310019)
摘    要:目的评价玉蜀黍苞叶和玉米棒各提取物的α-葡萄糖苷酶抑制活性。方法通过建立体外α-葡萄糖苷酶抑制模型,对玉蜀黍苞叶和玉米棒各提取物进行活性筛选,并对提取物浓度与抑制活性关系进行研究。结果玉蜀黍苞叶和玉米棒乙酸乙酯部位抑制α-葡萄糖苷酶活性(IC50=275.5和233.5mg/L)均高于阳性对照阿卡波糖(IC50=1 103.1mg/L),且苞叶乙酸乙酯部位抑制活性低于玉米棒乙酸乙酯部位。结论玉蜀黍苞叶和玉米棒乙酸乙酯部位均有好的α-葡萄糖苷酶抑制活性。

关 键 词:玉蜀黍  α-葡萄糖苷酶  抑制活性

α-Glucosidase inhibitory activity of extracts from the bracts and bars of Zea mays L.
YIN Zhen-hua,GU Xue-zhu,GU Hai-peng,KANG Wen-yi.α-Glucosidase inhibitory activity of extracts from the bracts and bars of Zea mays L.[J].Journal of Henan University,2012(2):88-90.
Authors:YIN Zhen-hua  GU Xue-zhu  GU Hai-peng  KANG Wen-yi
Institution:1(1.Institute of Chinese Materia,Henan University Kaifeng,Henan 475004,China;2.Institute of Chinese Materia Medical,Traditional Chinese Medical Research Institute,Beijing 100700,China)
Abstract:Objective To study the αglucosidase inhibitory activity of extracts from the bracts and bars of Zea mays L.Methods By establishing α-glucosidase inhibitory model in vitro,the activity of extracts from the bracts and bars of Z.mays L were screened.The relationship of inhibitory ratio and the extract concentration were also studied.Results The ethyl acetate extracts from the bracts and bars of Z.mays L had the higher inhibitor activity(IC50=275.5 and 233.5 mg/L) than that of acarbose(IC50=1 103.01 mg/L),and the ethyl acetate extracts from bracts had lower inhibitor activity than the bars.Conclusion The ethyl acetate extracts from the bracts and bars of Z.mays L have good α-glucosidase inhibitory activity.
Keywords:Zea mays L  α-glucosidase  Inhibitory activity
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