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VEGF-C及其受体Flt-4在肺鳞状细胞癌中的表达及其与淋巴结转移的关系
引用本文:范志勤,苏建萍,庞作良.VEGF-C及其受体Flt-4在肺鳞状细胞癌中的表达及其与淋巴结转移的关系[J].新疆医科大学学报,2011,34(8):812-816.
作者姓名:范志勤  苏建萍  庞作良
作者单位:新疆医科大学附属肿瘤医院胸外科,新疆,乌鲁木齐,830011
基金项目:新疆医科大学科技创新基金
摘    要:目的 探讨VEGF-C及其受体Flt-4在肺鳞状细胞癌中的表达及其与淋巴结转移的关系.方法 采用免疫组化S-P法检测89例肺鳞状细胞癌原发灶组织、癌旁组织中VEGF-C、Flt-4的表达,并分析其与临床病理特征的关系.结果 (1)VEGF-C和Flt-4在癌组织中和转移的淋巴结转移组中高表达(P<0.05);(2)在...

关 键 词:肺鳞状细胞癌  VEGF-C  Flt-4  淋巴结转移

Expression and clinical significance of VEGF-C and Flt-4 in squamous cell of lung cancer and the relation with the lymphnode metastasis
FAN Zhi-qin,SU Jian-ping,PANG Zuo-liang.Expression and clinical significance of VEGF-C and Flt-4 in squamous cell of lung cancer and the relation with the lymphnode metastasis[J].Journal of Xinjiang Medical University,2011,34(8):812-816.
Authors:FAN Zhi-qin  SU Jian-ping  PANG Zuo-liang
Institution:FAN Zhi-qin,SU Jian-ping,PANG Zuo-liang(Department of Thoracic Surgery,Affiliated Tumor Hospital,Xinjiang Medical University,Urumqi 830011,China)
Abstract:Objective To study the protein expression and clinical significance of VEGF-C and Flt-4 in squamous cell of lung cancer and the relation with the lymph node metastasis.MethodsVEGF-C and Flt-4 expression were evaluated in the primary and adjacent normal tissues of 89 patients with squamous cell of lung cancer as well as lymphnode metastasis tissues of 41 patients by immunohistoehemistry(S-P method).And analyse th relation to the clinic pathology.ResultsPositive expression rate of VEGF-C and Flt-4 in squamous...
Keywords:squamous cell of lung cancer  vascular endothelial growth factor c  vascular endothelial growth factor receptor-4  lymphnode metastasis  
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