新疆维、汉妇女宫颈癌发病危险因素的流行病学研究

目的:探讨新疆地区维吾尔族(维族)、汉族妇女宫颈癌发病特点在临床流行病学层面上有何不同以及发病率不同的危险因素之间有何差异。方法:采用回顾性流行病学问卷调查的形式,对1 482例维吾尔族、汉族住院患者(其中732例维吾尔族、汉族宫颈癌患者,750例非宫颈癌患者)进行临床流行病学调查。调查内容包括一般资料、既往病史、性行为和生育史、避孕史及吸烟史、生活习惯等。结果:维吾尔族妇女患宫颈癌危险因素(按OR值)排序为初次分娩年龄、初婚年龄、怀孕次数、月经期用材、家人是否吸烟和职业等因素。汉族妇女患宫颈癌危险因素(按OR值)排序为怀孕次数、丈夫是否做包皮术、家人是否吸烟、口服避孕药、初婚年龄和教育程度。维吾尔族、汉族妇女患宫颈癌既有共同的行为危险因素包括初婚年龄、被动吸烟、怀孕次数,又有各自不同的危险因素。结论:共同的危险因素在维、汉族妇女宫颈癌中的排序不同(按OR值),所起的作用不同。维吾尔族、汉族宫颈癌的发病率不同,有明显的临床流行病学差异。

Epidemiology study of risk factors on Uigur and Han cervical cancer in Xinjiang

Objective: To approach differences of morbidity characteristics and different risk factors of different incidence between Uigur and Han cervical cancer from the clinical epidemiology level in Xinjiang.Methods: Through the form of retrospective clinical epidemiological questionnaire for 1 482 cases of Uigur and Han patients,there were 732 cases of Uigur and Han patients with cervical cancer,750 cases of patients with non-cervical cancer were studied by clinical epidemiological investigation.The survey includes general information on past history,sexual and reproductive history,the history of contraception and smoking history,living habits,and so on.Results: The risk factors of Uigur women suffering from cervical cancer(OR by value) included by turn: the initial delivery of age,age at first marriage,the number of pregnancy,article for menstruation,family factors such as smoking and occupational.The risk factors of Han Chinese women suffering from cervical cancer(OR by value) were the number of pregnancy,whether or not to do foreskin excision about her husband,family smoking,oral contraceptives,the first marriage age and education level.Uigur and Han patients with cervical cancer had common risk factors such as the first marriage age,second-hand smoking and the number of pregnancy.And they also had different risk factors.Conclusions: The sorts of common risk factors were different between them(OR by value).It showed that their effects were also different.Each different risk factor was related with characteristics of invasion of each ethnical cervical cancer.It has obviously different characteristics of clinical epidemiology on the incidence rate of cervical cancer between Uigur and Han.