| 葡萄胶囊对化学性肝损伤保护作用的实验研究 |
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| 引用本文： | 马龙,刘涛,周晓辉.葡萄胶囊对化学性肝损伤保护作用的实验研究[J].新疆医科大学学报,2003,26(4):318-320. |
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| 作者姓名： | 马龙 刘涛 周晓辉 |
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| 作者单位： | 1. 新疆医科大学公共卫生学院,新疆,乌鲁木齐,830054
2. 新疆医科大学第一附属医院干部病房,新疆,乌鲁木齐,830054 |
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| 基金项目： | 新疆维吾尔自治区科委资助项目(编号 :2 0 0 0 2 ) |
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| 摘 要： | 目的：探讨葡萄胶囊对CCl4所致小鼠化学性肝损伤的保护作用。方珐：采用Alize自动生化仪测定四氯化碳(CCl4)所致小鼠化学性肝损伤动物模型的血清谷丙转氨酶(GPT)、谷草转氨酶(GOT)含量及白／球蛋白比例(A／G)；镜检观察肝脏病理组织学变化。结果：葡萄胶囊能明显降低四氯化碳(CCl4)所致肝损伤动物模型的血清GPT和GOT含量，并缓解肝损伤病理症状，对动物体重变化无影响。结论：葡萄胶囊对CCl4所致小鼠化学性肝损伤具有明显的保护作用。
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| 关 键 词： | 葡萄 胶囊 肝损伤 保护作用 |
| 文章编号： | 1009-5551(2003)04-0318-03 |
| 修稿时间： | 2003年2月25日 |
Study on protective action of grape capsules to the chemical liver damage |
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| MA Long,LIU Tao,ZHOU Xiao hui.Study on protective action of grape capsules to the chemical liver damage[J].Journal of Xinjiang Medical University,2003,26(4):318-320. |
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| Authors: | MA Long LIU Tao ZHOU Xiao hui |
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| Abstract: | Objective: To study the protective action of grape capsules on the chemical liver damage. Methods: The contents of GPT, GOT and albumin in mice's blood were determined by auto biochemistry. The pathological changes of liver were observed by microscope. Results: The GPT and GOT in blood of mice were significantly decreased in experimental group treated with grape capsules, when compared to the control group of liver damage model by CCl\-4. Moreover, the pathologic changes of liver damage were alleviated distinctly. Conclusion: The grape capsules have clear protective action to the mice's chemical liver damage by CCl\-4. |
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| Keywords: | grape capsule liver damage protective action |
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