| 前哨淋巴结活检在胃癌外科中临床意义的研究 |
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| 引用本文： | 王琦三,王海江,尹东,杨新辉,赵泽亮,方法.前哨淋巴结活检在胃癌外科中临床意义的研究[J].新疆医科大学学报,2010,33(2):180-182. |
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| 作者姓名： | 王琦三 王海江 尹东 杨新辉 赵泽亮 方法 |
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| 作者单位： | 新疆医科大学附属肿瘤医院腹外科,新疆,乌鲁木齐,830011 |
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| 摘 要： | 目的 探讨前哨淋巴结活检在胃癌外科中的临床应用及其意义.方法 术中在肿瘤四周的胃壁上注射亚甲蓝,第一个蓝染淋巴结,即前哨淋巴结(SLN),摘取所有前哨淋巴结并进行HE染色及细胞角蛋白免疫组化(IHC-CK)染色检查.结果 96例患者中92例成功检出前哨淋巴结,检出率为95.8%.在T1,T2期胃癌中,由SLN预测胃周淋巴结转移的准确率为93.8%(15/16),敏感性为87.5%(7/8),在T3期胃癌中,由SLN预测胃周淋巴结转移的准确率为67.1%(51/76),敏感性为52.8%(28/53).结论 术中使用亚甲蓝染色定位胃癌前哨淋巴结是安全可行的,前哨淋巴结的检出对胃癌淋巴结清扫范围的选择有一定意义.
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| 关 键 词： | 胃癌 前哨淋巴结活检 亚甲蓝 细胞角蛋白 |
A study on clinical significance of sentinel lymph node biopsy(SLNB) in gastric cancer surgery |
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| WANG Qi-san,WANG Hai-jiang,YIN Dong,et al.A study on clinical significance of sentinel lymph node biopsy(SLNB) in gastric cancer surgery[J].Journal of Xinjiang Medical University,2010,33(2):180-182. |
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| Authors: | WANG Qi-san WANG Hai-jiang YIN Dong |
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| Institution: | WANG Qi-san,WANG Hai-jiang,YIN Dong,et al(Department of Abdominal Surgery,Affiliated Tumor Hospital,Xinjiang Medical University,Urumqi 830011,China) |
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| Abstract: | Objective To investigate the clinical application and significance of sentinel lymph node biopsy in gastric cancer surgery.Methods Methylene blue was injected to the subserous layer around the primary tumor during the operation.The blue-stained lymph nodes that appeared first will be defined as SLN.All the SLNs were removed and examined by HE staining and IHC staining with cytokeratin monoclonal antibody.Results Among 96 cases included,the SLN was identified successfully in 92 cases.The detection rate was 9... |
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| Keywords: | gastric cancer sentinel lymph node biopsy methylene blue cytokeratin |
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