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左氧氟沙星注射液治疗泌尿系感染疗效分析
引用本文:韦晓静,樊小东,钱韶红.左氧氟沙星注射液治疗泌尿系感染疗效分析[J].中国医药导报,2011,8(22):82-83.
作者姓名:韦晓静  樊小东  钱韶红
作者单位:1. 河北省秦皇岛市中铁山桥集团医院药剂科,河北秦皇岛,066200
2. 河北省秦皇岛市工人医院内分泌科,河北秦皇岛,066200
摘    要:目的:在PK/PD参数理论指导下,观察左氧氟沙星静滴每日1次和每日2次治疗泌尿系感染的疗效。方法:选取86例泌尿系感染患者,随机分为治疗组和对照组,每组43例,治疗组用左氧氟沙星400 mg,静脉滴注,1次/d,对照组用左氧氟沙星200 mg,静脉滴注,2次/d。结果:用药3 d后两组血和尿中白细胞数、血中性粒细胞数及体温〉37℃的病例数比较,差异有统计学意义(P〈0.05)。其中,治疗组有效率为95.3%(41/43),对照组为83.7%(36/43),两组有效率比较,差异有统计学意义(P〈0.05)。结论:左氧氟沙星治疗泌尿系统感染,静滴每日1次给药疗效优于静滴每日2次。

关 键 词:左氧氟沙星  泌尿系感染  疗效  PK/PD参数

Curative efficacy analysis of Levofloxacin Injection in urinary system infection
WEI Xiaojing,FAN Xiaodong,QIAN Shaohong.Curative efficacy analysis of Levofloxacin Injection in urinary system infection[J].China Medical Herald,2011,8(22):82-83.
Authors:WEI Xiaojing  FAN Xiaodong  QIAN Shaohong
Institution:1.Department of Pharmacy,China Railway Shanhaiguan Bridge Group Hospital of Qinhuangdao City,Hebei Province,Qinhuangdao 066200,China;2.Deptment of Endocrinology,Worker′s Hospital of Qinhuangdao City,Hebei Province,Qinhuangdao 066200,China
Abstract:Objective: To observe the clinical efficiency of Levofloxacin ivgtt qd and bid in urinary system infection under the guide of PK/PD parameters theory.Methods: 86 cases of patients with urinary system infection were randomly divided into two groups,43 cases of patients in treatment group with Levofloxacin 400 mg ivgtt qd;43 cases of patients in control group with Levofloxacin 200 mg ivgtt bid.Results: The counting of WBC in urine and blood,neutrocyte in blood and the case of patients whose temperature over 3...
Keywords:Levofloxacin  Urinary tract infections  Therapeutic effect  PK/PD parameters  
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