| 中药复方对乳腺癌患者5年无病生存率及总生存率的影响 |
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| 引用本文： | 瞿文超,吴雪卿,冯佳梅,高晴倩,邵士珺,张婷婷,顾沐恩,梅章懿,陈小松,沈坤炜,万华.中药复方对乳腺癌患者5年无病生存率及总生存率的影响[J].中国医药导报,2012,9(36):120-122. |
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| 作者姓名： | 瞿文超 吴雪卿 冯佳梅 高晴倩 邵士珺 张婷婷 顾沐恩 梅章懿 陈小松 沈坤炜 万华 |
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| 作者单位： | 瞿文超 (上海中医药大学附属曙光医院中医乳腺科,上海,200021)； 吴雪卿 (上海中医药大学附属曙光医院中医乳腺科,上海,200021)； 冯佳梅 (上海中医药大学附属曙光医院中医乳腺科,上海,200021)； 高晴倩 (上海中医药大学附属曙光医院中医乳腺科,上海,200021)；邵士珺 (上海中医药大学附属曙光医院中医乳腺科,上海,200021)； 张婷婷 (上海中医药大学附属曙光医院中医乳腺科,上海,200021)；顾沐恩 (上海中医药大学附属曙光医院中医乳腺科,上海,200021)；梅章懿 (上海交通大学医学院附属瑞金医院乳腺疾病诊治中心,上海,200025)； 陈小松 (上海交通大学医学院附属瑞金医院乳腺疾病诊治中心,上海,200025)； 沈坤炜 (上海交通大学医学院附属瑞金医院乳腺疾病诊治中心,上海,200025)； 万华 (上海中医药大学附属曙光医院中医乳腺科,上海,200021)； |
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| 基金项目： | 上海市科研计划项目课题(编号编号:09ZR1432500);上海市教育委员会科研项目(项目编号:08CZ022) |
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| 摘 要： | 目的观察“乳癌术后方”对乳腺癌患者5年无病生存率以及总生存率的影响。方法2009年1月～2009年12月随访和统计592例乳腺癌患者，将其分为中药组352例和对照组240例。中药组患者须于术后1年内开始服用“乳癌术后方”，服药时间≥1年；对照组患者自乳腺癌术后至本次随访结束未曾服用“乳癌术后方”。结果中药组5年的无病生存率及总生存率均明显高于对照组，两组差异有统计学意义（DFS：9213％VS87．1％，P=0．009；OS：96．9％口589．6％，P〈0．0001）。结论“乳癌术后方”能提高乳腺癌患者5年的无病生存率以及总生存率，有效预防乳腺癌复发转移，延长乳腺癌患者的生存期。
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| 关 键 词： | 乳腺癌 无病生存期 总生存期 中药复方 |
Effect of compound traditional Chinese herbal medicine on rate of five year disease free survival and overall survival in breast cancer patients |
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| QU Wenchao,WU Xueqing,FENG Jiamei,GAO Qingqian,SHAO Shijun,ZHANG Tingting,GU Muen,MEI Zhangyi,CHEN Xiaosong,SHEN Kunwei,WAN Hua.Effect of compound traditional Chinese herbal medicine on rate of five year disease free survival and overall survival in breast cancer patients[J].China Medical Herald,2012,9(36):120-122. |
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| Authors: | QU Wenchao WU Xueqing FENG Jiamei GAO Qingqian SHAO Shijun ZHANG Tingting GU Muen MEI Zhangyi CHEN Xiaosong SHEN Kunwei WAN Hua |
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| Institution: | 1.Department of TCM Breast Surgery,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200021,China;2.Department of Breast Surgery,Ruijin Hospital Affiliated to School of Medicine of Shanghai Jiaotong University,Shanghai 200025,China |
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| Abstract: | Objective To observe the effect of ＂Ru＇ai Shuhou Recipe＂ （RSR） on 5 years disease-free survival （DFS） and overall survival （OS） in patients with breast cancer. Methods 592 patients with breast cancer were followed up and counted from January 2009 to December 2009, 352 patients in treatment group and 240 patients in control group. The patients in the treatment group must have been treated with RSR within one year after mastectomy for over one year. The patients in the control group were never treated with RSR until the end of follow-up. Results 5-year DFS and OS of treatment group were significantly higher than that of control group （DFS： 92.3% vs 87.1%,P = 0.009; OS： 96.9% vs 89.6%, P 〈 0.000 1）. Conclusion RSR can improve the 5-year DFS and OS prevent recurrence and metastasis, and extend the life of the pa- tients. |
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| Keywords: | Breast cancer Disease-free survival Overall survival Compound traditional Chinese medicine |
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