| 英夫利昔单抗与柳氮磺胺吡啶在克罗恩病中的疗效对比 |
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| 引用本文： | 滕忠平.英夫利昔单抗与柳氮磺胺吡啶在克罗恩病中的疗效对比[J].中国医药导报,2011,8(20):136-137. |
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| 作者姓名： | 滕忠平 |
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| 作者单位： | 湖南省麻阳苗族自治县红十字会医院内科,湖南麻阳,419400 |
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| 摘 要： | 目的：探讨比较英夫利昔单抗与柳氮磺胺吡啶在克罗恩病（CD）中的疗效及安全性。方法：将50例克罗恩病患者随机分为A组（英夫利昔单抗组）25例和B组（柳氮磺胺吡啶组）25例,后将两组患者的治疗总有效率、不良反应发生率及治疗前后的血沉、CRP（C反应蛋白）、唾液酸及α2球蛋白进行检测及比较。结果：A组总有效率（92.00%）高于B组（68.00%）,不良反应发生率低于B组（24.00%vs 36.00%）,而血沉、CRP、唾液酸及α2球蛋白均低于B组,P〈0.05或P〈0.01,有显著性或有非常显著性差异。结论：英夫利昔单抗在CD患者具有较佳的疗效。
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| 关 键 词： | 英夫利昔 柳氮磺胺吡啶 克罗恩病 疗效 |
The comparison on the effect of infliximab and salazosulfapyridine in crohn′s disease |
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| TENG Zhongping.The comparison on the effect of infliximab and salazosulfapyridine in crohn′s disease[J].China Medical Herald,2011,8(20):136-137. |
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| Authors: | TENG Zhongping |
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| Institution: | TENG Zhongping Department of Medicine,Red Cross Hospital of Mayang Miaozu Autonomous County,Hunan Province,Mayang 419400,China |
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| Abstract: | Objective：To study and compare the effect of infliximab and salazosulfapyridine in crohn＇s disease.Methods：50 patients with crohn＇s disease were randomly divided into group A（Infliximab group） 25 cases and group B（Salazosulfapyridine） 25 cases,then the total effective rate,incidence of adverse reaction and erythrocyte sedimentation rate,CRP,saili acid and α2-macroglobulin of two groups were detected and compared.Results：The total effective rate（92.00%） of group A was higher than that of group B（68.00%）,incidence of adverse reaction was lower than that of group B（24.00% vs 36.00%）,but erythrocyte sedimentation rate,CRP,saili acid and α2-macroglobulin were lower than those of group B,P0.05 or P0.01,there were significant differences or very significant differences.Conclusion：The effect of infliximab and salazosulfapyridine in crohn＇s disease is better. |
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| Keywords: | Infliximab Salazosulfapyridine Crohn's disease Effect |
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