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急性一氧化碳中毒后迟发性脑病60例临床分析
引用本文:吴强,马慧娟,路法枝,张皎皎.急性一氧化碳中毒后迟发性脑病60例临床分析[J].中国医药导报,2008,5(32):161-162.
作者姓名:吴强  马慧娟  路法枝  张皎皎
作者单位:1. 河南省新乡市中心医院神经内科,河南新乡,453000
2. 河南省新乡市第22中学校医务室,河南新乡,453000
摘    要:目的:研究急性一氧化碳中毒后迟发性脑病的发病机制及治疗。方法:本文回顾性分析了60例急性一氧化碳中毒后迟发性脑病患者的临床资料。结果:急性一氧化碳中毒后迟发性脑病临床表现复杂多样,以痴呆、精神症状、二便失禁为主,CT提示额、顶、枕叶皮质下白质密度降低。治疗主要为高压氧疗、激素、改善局部血液循环,有效率为89.1%,26.7%的患者可痊愈。结论:神经系统损害程度及预后与急性期吸入一氧化碳的浓度、昏迷时间长短、患者年龄、急性期是否及时行高压氧治疗、既往身体状况有关。

关 键 词:一氧化碳中毒  迟发性脑病

Clinical analysis on 60 patients with delayed encephalopathy after acute carbon monoxide poisoning
WU Qiang,MA Hui-juan,LU Fa-zhi,ZHANG Jiao-jiao.Clinical analysis on 60 patients with delayed encephalopathy after acute carbon monoxide poisoning[J].China Medical Herald,2008,5(32):161-162.
Authors:WU Qiang  MA Hui-juan  LU Fa-zhi  ZHANG Jiao-jiao
Institution:WU Qiang1,MA Hui-juan1,LU Fa-zhi1,ZHANG Jiao-jiao2
Abstract:Objective:To research the pathogenesis and treatments of delayed encephalopathy after acute carbon monoxide poisoning(DEACMP).Methods:Data were retrospectively analyzed on the 60 patients with DEACMP admitted to the hospital.Results:The main manifestation of DEACMP consisted of dementia,psychiatric symptoms and urinary and fecal incontinence.In computerized tomography(CT),it can be hinted that the density of white matter under the cerebral cortex of frontal lobe,parietal lobe and occipital lobe were decreased.The main treatments were hyperbaric oxygen therapy,hormone and improving the local blood circulation.The effective power was 89.1%and the cure rate was 26.7%.Conclusion:The damage of nervous system and prognosis are related to concentration of carbon monoxide breathed in by patients,the comatose time,a patient's age,whether or not having hyperbaric oxygen treatment promptly and previous physical status.
Keywords:Carbon monoxide poisoning  Delayed encephalopathy
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