| 三苯氧胺对乳腺癌围绝经期患者性激素水平的影响 |
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| 引用本文： | 杨新明,吴绍洋,陈莉丽,钟科峰,章汝霜.三苯氧胺对乳腺癌围绝经期患者性激素水平的影响[J].中国医药导报,2011,8(30):74-75. |
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| 作者姓名： | 杨新明 吴绍洋 陈莉丽 钟科峰 章汝霜 |
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| 作者单位： | 江西省南昌市第三医院(江西省乳腺专科医院)核医学科,江西南昌,330009 |
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| 基金项目： | 江西省南昌市科技支撑计划项目 |
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| 摘 要： | 目的：探讨三苯氧胺（TAM）对乳腺癌围绝经期患者性激素水平的影响。方法：选取200例围绝经期乳腺癌患者,分为服用及未服用TAM治疗组各100例,60例门诊健康体检围绝经期妇女为对照组,全都采用全自动化学发光法测定血清卵泡刺激素（FSH）、促黄体生成激素（LH）、雌二醇（E2）水平。结果：未服用TAM组与对照组FSH、LH、E2水平差异均无统计学意义（P〉0.05）;服用TAM组血清FSH、LH水平明显低于对照组和未服用TAM组,而E2含量却略高于对照组和未服用TAM组,差异有高度统计学意义（P〈0.01）。结论：服用TAM会明显影响乳腺癌围绝经期患者的性激素水平,临床应予以重视,以便让围绝经期乳腺癌患者得到更好、更及时的治疗,进一步提高其生存率。
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| 关 键 词： | 三苯氧胺 乳腺癌 围绝经期 性激素 |
Effect of Tamoxifen on sex hormone level of breast cancer patients at perimenopausal period |
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| YANG Xinming,WU Shaoyang,CHEN Lili,ZHONG Kefeng,ZHANG Rushuang.Effect of Tamoxifen on sex hormone level of breast cancer patients at perimenopausal period[J].China Medical Herald,2011,8(30):74-75. |
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| Authors: | YANG Xinming WU Shaoyang CHEN Lili ZHONG Kefeng ZHANG Rushuang |
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| Institution: | YANG Xinming,WU Shaoyang,CHEN Lili,ZHONG Kefeng,ZHANG Rushuang,Department of Nuclear Medicine,the Third Hospital of Nanchang City(Mastopathia Specialized Hospital of Jiangxi Province),Jiangxi Province,Nanchang 330009,China |
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| Abstract: | Objective:To explore the effect of Tamoxifen(TAM) on sex hormone level of breast cancer patients at perimenopausal period.Methods:200 patients with breast cancer at perimenopausal period were selected and they were separated into taking TAM group and not taking TAM group.60 healthy women at perimenopausal period in the out-patient department were selected as control group.Serum follicle stimulating hormone(FSH),luteinizing hormone(LH) and estradiol(E2) of the patients were assayed using full-automation chem... |
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| Keywords: | Tamoxifen Breast cancer Perimenopausal period Sex hormone |
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