| 小剂量奥美拉唑治疗功能性消化不良 |
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| 引用本文： | 李秋元,陈杰武,李郁声,汤盛新.小剂量奥美拉唑治疗功能性消化不良[J].中国医药导报,2011,8(16):90-92. |
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| 作者姓名： | 李秋元 陈杰武 李郁声 汤盛新 |
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| 作者单位： | 1. 汕头大学医学院附属第一医院消化科,广东汕头,515041
2. 汕头市潮南民生医院内二病区,广东汕头,515140 |
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| 摘 要： | 目的：观察小剂量奥美拉唑治疗功能性消化不良（FD）的临床疗效,探讨其临床意义。方法：将2010年3月～2011年3月在我院接受治疗的252例FD患者随机分为奥美拉唑组和莫沙必利组,奥美拉唑组给予小剂量奥美拉唑口服治疗,莫沙必利组给予莫沙必利口服治疗,观察两组治疗前后反酸、饱胀、上腹痛/不适积分情况、临床疗效及不良反应情况,并进行对比分析。结果：两组患者在治疗后反酸、饱胀、上腹痛/不适积分均较治疗前有显著下降,组内比较差异均有统计学意义;奥美拉唑组治疗后的反酸、上腹痛/不适积分明显低于莫沙必利组,组间比较差异有统计学意义（P〈0.05）;奥美拉唑组有效率高达94.44%,明显高于莫沙必利组的75.60%,组间比较差异有统计学意义（P〈0.05）;两组患者均未发现明显的不良反应。结论：小剂量奥美拉唑治疗FD能明显改善胃部烧灼感及腹痛感,临床疗效肯定,且具有服用方便、不良反应少等特点,是临床治疗FD的一种较佳药物,值得临床推广使用。
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| 关 键 词： | 功能性消化不良 奥美拉唑 莫沙必利 反酸 饱胀 上腹痛/不适 |
The treatment of low-dose Omeprazole for functional dyspepsia |
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| LI Qiuyuan,CHEN Jiewu,LI Yusheng,TANG Shengxiang.The treatment of low-dose Omeprazole for functional dyspepsia[J].China Medical Herald,2011,8(16):90-92. |
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| Authors: | LI Qiuyuan CHEN Jiewu LI Yusheng TANG Shengxiang |
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| Institution: | LI Qiuyuan1,CHEN Jiewu2,LI Yusheng2,TANG Shengxing2 1.Department of Gastroenterology,the First Affiliated Hospital of Shantou University Medical College,Shantou 515041,China,2.Second Ward Medicine,Chaonan Minsheng Hospital of Shantou City,Shantou 515140 |
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| Abstract: | Objective: To observe clinical efficacy of low-dose Omeprazole to functional dyspepsia,and analyze its clinical significance.Methods: 52 patients with FD treated in our hospital during March 2010-March 2011 were randomly divided into Omeprazole group and Mosapride group,Omeprazole group received low-dose oral Omeprazole treatment,and Mosapride group were given Mosapride oral treatment.Score of acid reflux,fullness,upper abdominal pain/discomfort points before and after the treatment as well as their clinica... |
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| Keywords: | Functional dyspepsia Omeprazole Mosapride Anti-acid Fullness Upper abdominal pain/discomfort |
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