| 日本毛连菜水洗部位降血糖、调节血脂作用研究 |
| |
| 引用本文： | 席啸虎,葛睿,高建平.日本毛连菜水洗部位降血糖、调节血脂作用研究[J].中国医药导报,2011,8(13):34-36. |
| |
| 作者姓名： | 席啸虎 葛睿 高建平 |
| |
| 作者单位： | 山西医科大学药学院,山西太原,030001 |
| |
| 摘 要： | 目的：探讨日本毛连菜水洗部位降血糖及调节血脂药理作用。方法：采用肾上腺素致小鼠生理性高血糖,以及四氧嘧啶致小鼠糖尿病等模型,观察日本毛连菜水洗部位对模型动物血糖、血清总胆固醇（TC）、三酰甘油（TG）、低密度脂蛋白（LDL-C）、高密度脂蛋白（HDL-C）的影响;采用比色法分析水洗部位的化学成分。结果：与模型组比较,日本毛连菜水洗部位低剂量显著降低四氧嘧啶致糖尿病小鼠血糖值（P〈0.05）,高剂量显著降低肾上腺素致糖尿病小鼠血糖值（P〈0.05）,给药组小鼠三酰甘油、低密度脂蛋白含量显著下降（P〈0.05）,高密度脂蛋白含量显著升高（P〈0.05）;水洗脱部位含多糖4 097 mg/100 g生药材,含黄酮913 mg/100 g生药材。结论：日本毛连菜水洗部位对糖尿病小鼠具有显著降血糖作用,同时可以调节糖尿病小鼠血脂水平。
|
| 关 键 词： | 日本毛连菜 四氧嘧啶 肾上腺素 降血糖 调节血脂 |
Study on the hypoglycemic and hypolipidemic effect of part eluated by water from Picris japonica Thunb |
| |
| XI Xiaohu,GE Rui,GAO Jianping.Study on the hypoglycemic and hypolipidemic effect of part eluated by water from Picris japonica Thunb[J].China Medical Herald,2011,8(13):34-36. |
| |
| Authors: | XI Xiaohu GE Rui GAO Jianping |
| |
| Institution: | XI Xiaohu,GE Rui,GAO Jianping School of Pharmacy,Shanxi Medical University,Shanxi Province,Taiyuan 030001,China |
| |
| Abstract: | Objective: To investigate the hypoglycemic and hypolipidemic effect of part eluated by water from Picris japonica Thunb.(WEW) on diabetic mice.Methods: The diabetic mice were established by injection of Alloxan or Epinephrine.Diabetic mice were given different dose of WEW.Mice's glucose value and blood serum TG,TC,HDL-C,LDL-C content were detected after 14 days.The chemical constituent of WEW was analyzed by colorimetric technique.Results: Compared with the diabete model group,the low WEW dose lowered allox... |
| |
| Keywords: | Picris japonica Thunb Alloxan Epinephrine Hypoglycemic Hypolipidemic |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
