| 异丙酚或异丙酚与氯胺酮合用对心血管的影响 |
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| 引用本文： | 吕志平,陈艳萍.异丙酚或异丙酚与氯胺酮合用对心血管的影响[J].湖南医科大学学报,2000,25(2):181-182. |
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| 作者姓名： | 吕志平 陈艳萍 |
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| 摘 要： | ３０例ＡＳＡ１～２级病人，分别静脉注射异丙酚２ｍｇ．ｋｇ＾－１（简称Ｐ组，ｎ＝１５），和静脉注射氯胺酮１ｍｇ．ｋｇ＾－１后再注射等同剂量的异丙酚（简称Ｋ＋Ｐ，ｎ＝１５），观察注药前、后１ｍｉｎ，３ｍｉｎ，５ｍｉｎ，１０ｍｉｎ的血流动力学变化。结果发现，Ｋ＋Ｐ组病人的血压下降较Ｐ组病人明显减轻。表明氯胺能较好地防治异丙酚所致的血压下降，又能加强其麻醉作用。
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| 关 键 词： | 异丙酚 氯胺酮 血流动力学 心血管 血压 |
Effect of propofol and propofol combined with ketamine on cardiovascular system] |
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| Z P Lü,Y P Chen,D Q Zou.Effect of propofol and propofol combined with ketamine on cardiovascular system][J].Bulletin of Hunan Medical University,2000,25(2):181-182. |
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| Authors: | Z P Lü Y P Chen D Q Zou |
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| Institution: | Department of Anensthesiology, Second Affiliated Hospital, Hunan Medical University, Changsha 410011. |
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| Abstract: | OBJECTIVE: To prevent blood pressure from reducing caused by injection of propofol. METHODS: Thirty patients, ASA Grade I-II, were randomly allocated into one of the two groups: Group I (Group P, n = 15) and Group II (Group K + P, n = 15), the patients received 2 mg.kg-1 propofol in Group I and 1 mg.kg-1 ketamine before equal dose of propofol in Group II. Systolic blood pressure(SBP), diastolic blood pressure(DBP), mean blood pressure and heart rate were measured before injection and 1 min, 3 min, 5 min and 10 min respectively after injection. RESULTS: Blood pressure in Group I was significantly lower than Group II. CONCLUSION: Ketamine can attenuate the hemodynamic responses to propofol. |
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