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米非司酮治疗异位妊娠47例
引用本文:刘凤英,张洪文.米非司酮治疗异位妊娠47例[J].湖南医科大学学报,1998,23(3):265-268.
作者姓名:刘凤英  张洪文
摘    要:为探讨米非司酮治疗异位妊娠的效果及适应症,将47例宫外孕分三组服药。结果29例有效,18例手术治疗。观察手术治疗者输卵管妊娠结局,腹腔出血量及病灶部位病理变化。分析原因,发现疗效与药物剂量,服药前血β-hCG高低及手术干预过早有关。认为大剂量米非司酮治疗异位妊娠具有简便、安全、无毒副作用等优点,是异位妊娠保守治疗的一种较好方法。适合于生命体征平稳,无剧烈腹痛,血β-hCG〈10ng·ml^-1,盆

关 键 词:异位妊娠  米非司酮  药物疗法

Mifepristone in the treatment of 47 ectopic pregnancy patients]
F Liu,H Zhang,Y Liu,Y Wu,G Tao,L Xu.Mifepristone in the treatment of 47 ectopic pregnancy patients][J].Bulletin of Hunan Medical University,1998,23(3):265-268.
Authors:F Liu  H Zhang  Y Liu  Y Wu  G Tao  L Xu
Institution:Department of Obstetrics and Gynecology, Second Affiliated Hospital, Hunan Medical University, Changsha.
Abstract:OBJECTIVE: To investigate the effect and indication of mifepristone in treating ectopic pregnancy, 47 patients were divided into three groups. RESULTS: Twenty-nine cases were effective; 18 cases were ineffective and operated on in which we observed the gestational termination, bleeding capacity, and pathological changes in fallopian tube. We found that the effect was related to the drug dosage, levels of beta-hCG in blood and the operating time. CONCLUSION: High dosage of mifepristone in treating ectopic pregnancy is convenient, safe, and has no side-effects. It is suitable for patients with early ectopic pregnancy who have smooth life-sign, beta-hCG < 10 ng.ml-1, the mass in pelvic cavity < or = 5 cm, without acute belly-ache and pulsation of fetal heart in fallopian tube and who ask for the conservative treatment.
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