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体外循环时间对胃粘膜Pco2,胃粘膜pH的影响
引用本文:刘瑶,郭曲练.体外循环时间对胃粘膜Pco2,胃粘膜pH的影响[J].湖南医科大学学报,1998,23(2):152-154.
作者姓名:刘瑶  郭曲练
摘    要:将16例心内直视手术病人按体外循环(CPB)时间分为短于100min(A组)及超过100min(B组)两组,以观察CPB时间对胃粘膜Pco2及胃粘膜pH(pHi)的影响。结果显示,停机前两组病人胃粘膜Pco2显著增高,pHi显著降低,尤以B组为著。术后A组未见并发症,B组3例病人发生致命并发症,其中1例死亡。提示低温CPB时间越长,胃粘膜酸中毒越重,术后可能发生致命并发症。

关 键 词:体外循环  胃粘膜  酸中毒  并发症

Influence of cardiopulmonary bypass time on gastric intramucosal Pco2 and pH]
Y Liu,Q Guo,H Cai.Influence of cardiopulmonary bypass time on gastric intramucosal Pco2 and pH][J].Bulletin of Hunan Medical University,1998,23(2):152-154.
Authors:Y Liu  Q Guo  H Cai
Institution:Department of Anesthesiology, Xiangya Hospital, Hunan Medical University, Changsha.
Abstract:To determine the influence of cardiopulmonary bypass time on gastric intramucosal Pco2 and pH (pHi), 16 patients undergoing cardiopulmonary bypass (CPB) were divided into two groups according to the CPB time-- group A (n = 8) within 100 minutes and group B (n = 8) beyond 100 minutes. The gastric intramucosal Pco2 increased and the pHi decreased significantly (P< 0.01) at the end CPB compared with before operation, before bypass and 30 minutes after intermission of CPB in all patients. Between group B and A, there were significant differences in the gastric intramucosal Pco2 and in the pHi at the end of CPB. The patients of group A had no severe complications. In group B, three patients developed life-threatening complications, one of them died. The results indicate that the longer the CPB time, the greater the degree of gastric mucosal acidosis. It predicts the patients may develop life-threatening complication after cardiac operations.
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