肝癌肝动脉化疗栓塞前后门脉供血的变化

用双螺旋ＣＴ血管成像技术研究巨块型肝癌肝动脉化疗栓塞前后门脉对肿瘤血供的变化及门脉供血对化疗栓塞（ＴＡＣＥ）治疗的影响。结果显示，门脉对巨块型肝癌的供血主要位于肿块周边部，经ＴＡＣＥ治疗后肿块周边部门脉血供增加（Ｐ〈０．０５），且与肿块缩小程度呈负相关（ｒ＝０．７９，Ｐ〈０．０１）。提示门脉对肿块供血明显者有必要行门脉途径介入治疗。

Changes of blood supply from portal system after transcatheter arterial chemoembolization in huge hepatocellular carcinoma]

OBJECTIVE: Blood supply changes of the portal venous system to the tumor mass before and after transcatheterarterial chemoembolization(TACE) in a series of 22 patients with huge hepatocellular carcinoma were monitored to study the necessity of intervention via portal vein. METHODS: Twenty-two selected patients with huge hepatocellular carcinoma were enrolled in the study. Elscint double helical CT was used to scan liver during the maximum concentration of contrast medium in portal venous system. CT Angiography and MIP(Maximum Intensity Projection) were used to image formation of the portal venous system. RESULTS: The technique of scan and image formation were excellent to evaluate the attribution of portal venous blood supply to HCC. The portal venous blood supply was mainly the tumor periphery distribution (P < 0.01). After treatment of TACE, the portal venous blood supply to tumor periphery increased significantly (P < 0.05), and some did appear signs of enriched blood supply around the tumor. Negative correlation between the degree of reduction in tumor and portal venous blood supply to the tumor periphery before TACE was evident. CONCLUSION: The attribution of portal venous blood supply to HCC was in the tumor periphery, and regression of tumor after TACE was affected by portal venous blood supply to the tumor, thus it is reasonable to suggest interventional therapy via portal vein.