| Effects of WH-1 and WH-2 eye drops on experimental allergic uveitis in rabbits |
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| 作者姓名： | 胡士星 李绍珍 谢楚芳 潘苏华 黄祥坤 毛文书 |
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| 作者单位： | Department of Ophthalmology First Military Medical University，Guangzhou 510515，Zhongshan Ophthalmic Center，Sun Yat-sen University of Medical Sciences，Guangzhou 510000，Zhongshan Ophthalmic Center，Sun Yat-sen University of Medical Sciences，Guangzhou 510000，Zhongshan Ophthalmic Center，Sun Yat-sen University of Medical Sciences，Guangzhou 510000，Zhongshan Ophthalmic Center，Sun Yat-sen University of Medical Sciences，Guangzhou 510000，Zhongshan Ophthalmic Center，Sun Yat-sen University of Medical Sciences，Guangzhou 510000 |
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| 摘 要： | Effects of WH-1 and WH-2 eye drops on experimental allergic uveitis(FAU)in rabbits induced by bovine serum albumin were clinically and pathologically observed in comparisonwith local drops of dexamethasone used as positive control.The results showed that WH-2 obvi-ously inhibited the inflammatory reactions while WH-1 did not.Protein concenwation in the aqueoushumor of WH-2-treated group of rabbits was 9.24±2.34mg/ml,which was notably lower(P<0.01)than both that of the untreated(14.33±3.14 mg/ml)and of the WH-1-treated(12.91±3.95mg/ml),but signifificantly higher than that of the dexame dexamethasone-treated goup(4.43±1.43mg/ml,P<0.01).The alleviation of the intraocular inflammatory reaction by therapy of WH-2eye drops was confimed pathologically.This study indicates that WH-2 has a positiveantiphlogistic effect on EAU in rabbits.
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Effects of WH-1 and WH-2 eye drops on experimental allergic uveitis in rabbits |
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| Hu Shixing,Li Shaozhen,Xie Chufarg,Pan Suhua,Huarg Xiargkun,Mao Wenshu Delpartment of Ophthalmology,First Military Medical University Guangzhou Zhongshan Ophthalmic Center,Sun Yat-sen University of Medical Sciences,Guangzhou.Effects of WH-1 and WH-2 eye drops on experimental allergic uveitis in rabbits[J].Journal of Medical Colleges of PLA(China),1992(2). |
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| Authors: | Hu Shixing Li Shaozhen Xie Chufarg Pan Suhua Huarg Xiargkun Mao Wenshu Delpartment of Ophthalmology First Military Medical University Guangzhou Zhongshan Ophthalmic Center Sun Yat-sen University of Medical Sciences Guangzhou |
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| Institution: | Hu Shixing,Li Shaozhen,Xie Chufarg,Pan Suhua,Huarg Xiargkun,Mao Wenshu Delpartment of Ophthalmology,First Military Medical University Guangzhou 510515 Zhongshan Ophthalmic Center,Sun Yat-sen University of Medical Sciences,Guangzhou 510000 |
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| Abstract: | |
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| Keywords: | WH-1 and WH-2 eye drops experimental allergic uveitis(FAU) animal rabbits |
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